MARCH1 抗体
(Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1))
MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al., 2004 [PubMed 14722266]\; Thibodeau et al., 2008 [PubMed 18389477]\; De Gassart et al., 2008 [PubMed 18305173]).[supplied by OMIM, Mar 2010].
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MARCH1
适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Bat, 小鸡, 猴
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our MARCH1 抗体
: "The E3 ubiquitin ligase MARCH1 mediates downregulation of plasma membrane GABAB receptors under ischemic conditions by inhibiting fast receptor recycling." in: Scientific reports, Vol. 15, Issue 1, pp. 1330, (2025) (PubMed).: "Intervention of Gastrodin in Type 2 Diabetes Mellitus and Its Mechanism." in: Frontiers in pharmacology, Vol. 12, pp. 710722, (2021) (PubMed).
: "Novel regulation of MHC class II function in B cells." in: The EMBO journal, Vol. 26, Issue 3, pp. 846-54, (2007) (PubMed).
Aliases for MARCH1 抗体
membrane associated ring-CH-type finger 1 (MARCH1) 抗体membrane-associated ring finger (C3HC4) 1 (March1) 抗体
membrane associated ring-CH-type finger 1 (March1) 抗体
2900024D24Rik 抗体
BB085186 抗体
DKFZp459K1250 抗体
MARCH-I 抗体
MARCH1 抗体
RGD1305148 抗体
RNF171 抗体
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