MAFA 产品
(Transcription Factor MafA (MAFA))
Categories
MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS\; MIM 176730) (Olbrot et al., 2002 [PubMed 12011435]).[supplied by OMIM, Mar 2008].
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Featured MAFA Categories
Recommended MAFA 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN567058
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (p), IHC (p)
Validations
- (1)
Cat. No.
ABIN729898
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7254463
Quantity
200 μL
Datasheet
Datasheet
Recommended MAFA 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (3)
Cat. No.
ABIN3083372
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310007
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3125943
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our MAFA Products
: "B lymphocytes protect islet β cells in diabetes prone NOD mice treated with imatinib." in: JCI insight, Vol. 5, (2019) (PubMed).: "The Pdx1 Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β Cell Function." in: Diabetes, (2019) (PubMed).
: "LIM-domain transcription complexes interact with ring-finger ubiquitin ligases and thereby impact islet β-cell function." in: The Journal of biological chemistry, Vol. 294, Issue 31, pp. 11728-11740, (2019) (PubMed).
: "mTORC1 to AMPK switching underlies β-cell metabolic plasticity during maturation and diabetes." in: The Journal of clinical investigation, Vol. 130, (2019) (PubMed).
: "Vitamin D Switches BAF Complexes to Protect β Cells." in: Cell, Vol. 173, Issue 5, pp. 1135-1149.e15, (2018) (PubMed).
: "Origin and Segmental Diversity of Spinal Inhibitory Interneurons." in: Neuron, Vol. 97, Issue 2, pp. 341-355.e3, (2018) (PubMed).
: "Defining a Novel Role for the PDX1 Transcription Factor in Islet β Cell Maturation and Proliferation During Weaning." in: Diabetes, (2017) (PubMed).
: "Feedback inhibition of CREB signaling promotes beta cell dysfunction in insulin resistance." in: Cell reports, Vol. 10, Issue 7, pp. 1149-57, (2015) (PubMed).
: "MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function." in: Diabetes, Vol. 64, Issue 11, pp. 3772-83, (2015) (PubMed).
: "Constitutive role of GADD34 and CReP in cancellation of phospho-eIF2α-dependent translational attenuation and insulin biosynthesis in pancreatic β cells." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 20, Issue 11, pp. 871-86, (2015) (PubMed).
Synonyms and alternative names related to MAFA
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian) (Mafa), MAF bZIP transcription factor A (MAFA), MAF bZIP transcription factor A (Mafa), killer cell lectin-like receptor subfamily G, member 1 (Klrg1), v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A (mafa), v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa (mafaa), monocyte to macrophage differentiation-associated (Mmd), 2F1-Ag, hMafA, L-MAF, Maf, MAFA, MAFA-L, mafl, MAFL, RGD1562627, RIPE3b1, SMaf1Protein level used designations for MAFA
- Mafa homolog
- V-maf musculoaponeurotic fibrosarcoma oncogene homolog A
- pancreatic beta-cell-specific transcriptional activator
- transcription factor MafA
- transcription factor RIPE3b1
- v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A
- v-maf musculoaponeurotic fibrosarcoma oncogene homolog A
- killer cell lectin-like receptor subfamily G member 1
- mast cell function-associated antigen 2F1
- Transcription factor MafA
- leucine zipper transcription factor
- somite Maf1
- v-maf musculoaponeurotic fibrosarcoma oncogene family, protein L
- bZIP transcription factor L-Maf
- lens-specific Maf
- macrophage/microglia activation-associated factor
- monocyte to macrophage differentiation factor
- monocyte to macrophage differentiation protein
- progestin and adipoQ receptor family member XI
- LOW QUALITY PROTEIN: transcription factor MafA
- v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
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