EDG-6
S1PR4
WB, PC
Whole Cell Lysate
产品编号 ABIN924992
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for EDG-6 (ABIN924992)
抗原
S1PR4
(Sphingosine-1-Phosphate Receptor 4 (S1PR4))
应用范围
Western Blotting (WB), Positive Control (PC)
Lysate Fraction
Whole Cell Lysate
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应用备注
- For use as a positive control with EDG-6 polyclonal antibody ABIN187788 for Western blot analysis. Use 10-20 µl of EDG-6 cell lysate per lane as a control when using EDG-6 antibody.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Provided in 10% glycerol, 063 M Tris-HCl (pH 6.8), 2% SDS and 0.002% bromophenol blue and 5% 2-mercaptoethanol.
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储存条件
- -20 °C
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- S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))
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别名
- EDG-6
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背景
- EDG-6 Trnasfected Cell Positive Control Lysate. EDG-6 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-6 is a sphingosine-1- phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion, and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG-6 is expressed in lymphoid and hematopoietic tissue and in the lungs.
抗原
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