(Latent Transforming Growth Factor beta Binding Protein 1 (LTBP1))
The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Weil, van den Bruck, Ziegenhals, Juranek, Goedde, Orth, Wirth, Jenke, Postberg: "β6 integrinosis: a new lethal autosomal recessive ITGB6 disorder leading to impaired conformational transitions of the αVβ6 integrin receptor." in: Gut, (2019) (PubMed).
Kang, Yeom, Kim, Kim, Lee: "Expression profiling of more than 3500 proteins of MSS-type colorectal cancer by stable isotope labeling and mass spectrometry." in: Journal of proteomics, Vol. 75, Issue 10, pp. 3050-62, (2012) (PubMed).
Saraon, Musrap, Cretu, Karagiannis, Batruch, Smith, Drabovich, Trudel, van der Kwast, Morrissey, Jarvi, Diamandis: "Proteomic profiling of androgen-independent prostate cancer cell lines reveals a role for protein S during the development of high grade and castration-resistant prostate cancer." in: The Journal of biological chemistry, Vol. 287, Issue 41, pp. 34019-31, (2012) (PubMed).
Aliases for LTBP1 抗体
latent transforming growth factor beta binding protein 1 S homeolog (ltbp1.S) 抗体 latent transforming growth factor beta binding protein 1 (ltbp1) 抗体 latent transforming growth factor beta binding protein 1 (LTBP1) 抗体 latent transforming growth factor beta binding protein 2 (LTBP2) 抗体 latent TGFbeta binding protein (LTBP1) 抗体 latent-transforming growth factor beta-binding protein 1 (LOC100542113) 抗体 latent transforming growth factor beta binding protein 1 (Ltbp1) 抗体 9430031G15Rik 抗体 9830146M04 抗体 b2b1000Clo 抗体 Ltbp-1 抗体 LTBP1 抗体 ltgf-1 抗体 Tgfb 抗体