This gene is significantly downregulated in primary brain tumors. The exact function of the protein encoded by this gene is unknown. [provided by RefSeq, Jul 2008].
Gao, Liang, Lu, Wang, Xia, Yuan, Yao, Wang, Tan, Laurence, Xu, Yu, Xiao, Chen, Zhou, Zhang, Chen, Chen: "Global analysis of DNA methylation in hepatocellular carcinoma by a liquid hybridization capture-based bisulfite sequencing approach." in: Clinical epigenetics, Vol. 7, Issue 1, pp. 86, (2015) (PubMed).
Soto, Watkins, Johnson, Schottler, Kerschensteiner: "NGL-2 regulates pathway-specific neurite growth and lamination, synapse formation, and signal transmission in the retina." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 29, pp. 11949-59, (2013) (PubMed).
DeNardo, de Wit, Otto-Hitt, Ghosh: "NGL-2 regulates input-specific synapse development in CA1 pyramidal neurons." in: Neuron, Vol. 76, Issue 4, pp. 762-75, (2012) (PubMed).
Zhang, Rajan, Savelieva, Wang, Vogel, Kelly, Xu, Hasson, Jarman, Lanthorn: "Netrin-G2 and netrin-G2 ligand are both required for normal auditory responsiveness." in: Genes, brain, and behavior, Vol. 7, Issue 4, pp. 385-92, (2008) (PubMed).