(Loss of Heterozygosity, 12, Chromosomal Region 1 (LOH12CR1))
As part of a BORC-like complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, this complex may couple lysosomes to microtubule plus-end-directed kinesin motor. {ECO:0000250|UniProtKB:Q969J3}.
Farías, Guardia, De Pace, Britt, Bonifacino: "BORC/kinesin-1 ensemble drives polarized transport of lysosomes into the axon." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 14, pp. E2955-E2964, (2018) (PubMed).
Aliases for LOH12CR1 抗体
BLOC-1 related complex subunit 5 (Borcs5) 抗体 BLOC-1 related complex subunit 5 (BORCS5) 抗体 5830457J20Rik 抗体 AW124643 抗体 LOH1CR12 抗体