LMTK2 抗体
(Lemur tyrosine Kinase 2 (LMTK2))
The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis. [provided by RefSeq, Oct 2009].
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Latest Publications for our LMTK2 抗体
: "Lemur Tyrosine Kinase 2, a novel target in prostate cancer therapy." in: Oncotarget, Vol. 6, Issue 16, pp. 14233-46, (2015) (PubMed).: "Association of 17 prostate cancer susceptibility loci with prostate cancer risk in Chinese men." in: The Prostate, Vol. 70, Issue 4, pp. 425-32, (2010) (PubMed).
: "Involvement of BREK, a serine/threonine kinase enriched in brain, in NGF signalling." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 9, Issue 3, pp. 219-32, (2004) (PubMed).
: "The DNA sequence of human chromosome 7. ..." in: Nature, Vol. 424, Issue 6945, pp. 157-64, (2003) (PubMed).
: "Human chromosome 7: DNA sequence and biology. ..." in: Science (New York, N.Y.), Vol. 300, Issue 5620, pp. 767-72, (2003) (PubMed).
Aliases for LMTK2 抗体
lemur tyrosine kinase 2 (LMTK2) 抗体lemur tyrosine kinase 2 (Lmtk2) 抗体
2900041G10Rik 抗体
A330101P12Rik 抗体
AATYK2 抗体
aatyk2 抗体
BREK 抗体
cprk 抗体
KPI-2 抗体
KPI2 抗体
LMR2 抗体
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