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LIPE 产品

(Lipase, Hormone-Sensitive (LIPE))
The protein encoded by this gene has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids. [provided by RefSeq, Jul 2008].

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Featured LIPE Categories

LIPE 抗体

High quality antibodies with extensive validation data.

LIPE ELISA试剂盒

Reliable ELISA kits for a wide range of species.

LIPE 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LIPE 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6255406
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6256370
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro)
Validations
  • (2)
Cat. No. ABIN743108
Quantity 100 μL
Datasheet Datasheet

Recommended LIPE ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968314
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957494
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957495
Quantity 96 tests
Datasheet Datasheet

Recommended LIPE 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093530
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3119807
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7393655
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our LIPE Products

Xu, Chang, Jung, Moro, Chou, King, Hines, Sinnett-Smith, Rozengurt, Eibl: "Deficiency in hormone-sensitive lipase accelerates the development of pancreatic cancer in conditional KrasG12D mice." in: BMC cancer, Vol. 18, Issue 1, pp. 797, (2019) (PubMed).

Smagris, BasuRay, Li, Huang, Lai, Gromada, Cohen, Hobbs: "Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis." in: Hepatology (Baltimore, Md.), Vol. 61, Issue 1, pp. 108-18, (2014) (PubMed).

Hagopian, Tomilov, Tomilova, Kim, Taylor, Lam, Cortopassi, McDonald, Ramsey: "Shc proteins influence the activities of enzymes involved in fatty acid oxidation and ketogenesis." in: Metabolism: clinical and experimental, Vol. 61, Issue 12, pp. 1703-13, (2012) (PubMed).

Aboulaich, Ortegren, Vener, Strålfors: "Association and insulin regulated translocation of hormone-sensitive lipase with PTRF." in: Biochemical and biophysical research communications, Vol. 350, Issue 3, pp. 657-61, (2006) (PubMed).

Ortegren, Yin, Ost, Karlsson, Nystrom, Strålfors: "Separation and characterization of caveolae subclasses in the plasma membrane of primary adipocytes; segregation of specific proteins and functions." in: The FEBS journal, Vol. 273, Issue 14, pp. 3381-92, (2006) (PubMed).

Yeaman: "Hormone-sensitive lipase--new roles for an old enzyme." in: The Biochemical journal, Vol. 379, Issue Pt 1, pp. 11-22, (2004) (PubMed).

Kraemer, Shen, Harada, Patel, Osuga, Ishibashi, Azhar: "Hormone-sensitive lipase is required for high-density lipoprotein cholesteryl ester-supported adrenal steroidogenesis." in: Molecular endocrinology (Baltimore, Md.), Vol. 18, Issue 3, pp. 549-57, (2004) (PubMed).

Sekiya, Osuga, Okazaki, Yahagi, Harada, Shen, Tamura, Tomita, Iizuka, Ohashi, Okazaki, Sata, Nagai, Fujita, Shimano, Kraemer, Yamada, Ishibashi: "Absence of hormone-sensitive lipase inhibits obesity and adipogenesis in Lep ob/ob mice." in: The Journal of biological chemistry, Vol. 279, Issue 15, pp. 15084-90, (2004) (PubMed).

Holst, Langin, Mulder, Laurell, Grober, Bergh, Mohrenweiser, Edgren, Holm: "Molecular cloning, genomic organization, and expression of a testicular isoform of hormone-sensitive lipase." in: Genomics, Vol. 35, Issue 3, pp. 441-7, (1996) (PubMed).

Kraemer, Patel, Saedi, Sztalryd: "Detection of hormone-sensitive lipase in various tissues. I. Expression of an HSL/bacterial fusion protein and generation of anti-HSL antibodies." in: Journal of lipid research, Vol. 34, Issue 4, pp. 663-71, (1993) (PubMed).

Synonyms and alternative names related to LIPE

FYN binding protein 1 (FYB1), lipase E, hormone sensitive type (LIPE), lipase E, hormone sensitive type (Lipe), lipase, hormone-sensitive (LIPE), lipase, hormone-sensitive (lipe), lipase, hormone-sensitive L homeolog (lipe.L), lipase, hormone sensitive (Lipe), Hormone-sensitive lipase (Hsl), lipase, hormone-sensitive a (lipea), 4933403G17Rik, A, ADAP, anon-56Ea, CG11055, dHSL, Dmel\CG11055, HSL, hsl, LHS, LIPE, lipe, PRO0823, si:dkey-3n22.7, SLAP-130

Protein level used designations for LIPE

  • FYB-120/130
  • FYN-T-binding protein
  • FYN-binding protein
  • SLP-76-associated phosphoprotein
  • adhesion and degranulation-promoting adaptor protein
  • p120/p130
  • hormone-sensitive lipase
  • hormone-sensitive lipase testicular isoform
  • hormone - sensitive lipase testicular isoform
  • lipase E
  • lipase, hormone-sensitive
  • hormone-sensitive lipase-like
  • CG11055 gene product from transcript CG11055-RB
  • CG11055-PA
  • CG11055-PB
  • CG11055-PC
  • Hormone-sensitive lipase ortholog
  • Hsl-PA
  • Hsl-PB
  • Hsl-PC
  • hormone sensitive lipase
  • transcription unit A
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