LIN28B 蛋白
(Lin-28 Homolog B (LIN28B))
The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012].
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5 results
LIN28B
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 90 % as determined by SDS-PAGE.
ELISA, WB
Aliases for LIN28B 蛋白
lin-28 homolog B (LIN28B) 蛋白lin-28 homolog B (lin28b) 蛋白
lin-28 homolog B S homeolog (lin28b.S) 蛋白
lin-28 homolog B (C. elegans) (Lin28b) 蛋白
lin-28 homolog B (C. elegans) (LIN28B) 蛋白
lin-28 homolog B (Lin28b) 蛋白
2810403D23Rik 蛋白
csdd2 蛋白
CSDD2 蛋白
D030047M17Rik 蛋白
LIN-28 蛋白
Lin-28.2 蛋白
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