LILRA3 抗体
(Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3))
Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997 [PubMed 9548455]).[supplied by OMIM, Mar 2008].
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Latest Publications for our LILRA3 抗体
: "Soluble LILRA3 promotes neurite outgrowth and synapses formation through a high-affinity interaction with Nogo 66." in: Journal of cell science, Vol. 129, Issue 6, pp. 1198-209, (2016) (PubMed).: "Serum Leukocyte Immunoglobulin-Like Receptor A3 (LILRA3) Is Increased in Patients with Multiple Sclerosis and Is a Strong Independent Indicator of Disease Severity; 6.7kbp LILRA3 Gene Deletion Is Not ..." in: PLoS ONE, Vol. 11, Issue 2, pp. e0149200, (2016) (PubMed).
: "TLR8 regulation of LILRA3 in monocytes is abrogated in human immunodeficiency virus infection and correlates to CD4 counts and virus loads." in: Retrovirology, Vol. 13, pp. 15, (2016) (PubMed).
: "Glycosylation in a mammalian expression system is critical for the production of functionally active leukocyte immunoglobulin-like receptor A3 protein." in: The Journal of biological chemistry, Vol. 288, Issue 46, pp. 32873-85, (2013) (PubMed).
: "Soluble LILRA3, a potential natural antiinflammatory protein, is increased in patients with rheumatoid arthritis and is tightly regulated by interleukin 10, tumor necrosis factor-alpha, and ..." in: The Journal of rheumatology, Vol. 37, Issue 8, pp. 1596-606, (2010) (PubMed).
: "DNA sequence variation and molecular genotyping of natural killer leukocyte immunoglobulin-like receptor, LILRA3." in: Immunogenetics, Vol. 55, Issue 3, pp. 165-71, (2003) (PubMed).
: "A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 159, Issue 11, pp. 5192-6, (1998) (PubMed).
: "Molecular identification of a novel family of human Ig superfamily members that possess immunoreceptor tyrosine-based inhibition motifs and homology to the mouse gp49B1 inhibitory receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 159, Issue 5, pp. 2342-9, (1997) (PubMed).
Aliases for LILRA3 抗体
leukocyte immunoglobulin like receptor A3 (LILRA3) 抗体CD85E 抗体
e3 抗体
HM31 抗体
HM43 抗体
ILT-6 抗体
ILT6 抗体
LIR-4 抗体
LIR4 抗体
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