LIG4 蛋白
(Ligase IV, DNA, ATP-Dependent (LIG4))
The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| LIG4 Protein (AA 1-911) (His tag) | 小鼠 | HEK-293 Cells |
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| LIG4 Protein (AA 1-911) (His tag) | 人 | HEK-293 Cells |
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| LIG4 Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| LIG4 Protein (AA 2-210) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| LIG4 Protein (AA 1-911) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| LIG4 Protein (AA 1-911) (Strep Tag) | 小鼠 | Cell-free protein synthesis (CFPS) |
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| LIG4 Protein (AA 724-911) (His-IF2DI Tag) | 人 | 大肠杆菌（E. Coli） |
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| LIG4 Protein (AA 1-609) (His tag) | 人 | Bacteria |
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| LIG4 Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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Protein
- PS (Protein Structure: 有验证图片)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Protein
- PS (Protein Structure: 有验证图片)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Protein
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Aliases for LIG4 蛋白
ligase IV, DNA, ATP-dependent (lig4) 蛋白DNA ligase 4 (LIG4) 蛋白
DNA ligase 4 (LOC100212302) 蛋白
DNA ligase 4 (CpipJ_CPIJ005161) 蛋白
DNA ligase 4 (PTRG_09982) 蛋白
DNA ligase 4 (MCYG_05151) 蛋白
DNA ligase 4 (LOC657210) 蛋白
ATP-dependent DNA ligase implicated in dsDNA break repair via nonhomologous end-joining (LIG4) 蛋白
DNA ligase IV (ATLIG4) 蛋白
ligase IV, DNA, ATP-dependent L homeolog (lig4.L) 蛋白
ligase IV, DNA, ATP-dependent (Lig4) 蛋白
DNA ligase 4 (Lig4) 蛋白
5830471N16Rik 蛋白
DNA LIGASE IV 蛋白
DNL4 蛋白
lig4 蛋白
LIG4 蛋白
lig4-A 蛋白
tiny 蛋白
zgc:165595 蛋白
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