LIG3 抗体
(Ligase III, DNA, ATP-Dependent (LIG3))
This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
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45 results :
KO Validated
LIG3
适用: 人
WB, IF, ICC
宿主: 兔
Polyclonal
unconjugated
1 reference
LIG3
适用: 人, 小鼠, 大鼠
WB, ELISA, IHC, IF, ICC
宿主: 兔
Polyclonal
unconjugated
LIG3
适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Bat, Hamster, 猴
WB
宿主: 兔
Polyclonal
unconjugated
1 image
LIG3
适用: 人, 小鼠, 大鼠, 马, 兔, 豚鼠, Cow, Bat
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our LIG3 抗体
: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).: "PAXX Is an Accessory c-NHEJ Factor that Associates with Ku70 and Has Overlapping Functions with XLF." in: Cell reports, Vol. 17, Issue 2, pp. 541-555, (2016) (PubMed).
: "SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner." in: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 2, pp. 269-76, (2015) (PubMed).
: "DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair." in: Nucleic acids research, Vol. 43, Issue 2, pp. 875-92, (2015) (PubMed).
: "Age-dependent decline of DNA base excision repair activity in rat cortical neurons." in: Mechanisms of ageing and development, Vol. 133, Issue 4, pp. 186-94, (2012) (PubMed).
: "Widespread dependence of backup NHEJ on growth state: ramifications for the use of DNA-PK inhibitors." in: International journal of radiation oncology, biology, physics, Vol. 79, Issue 2, pp. 540-8, (2011) (PubMed).
: "Arsenicals affect base excision repair by several mechanisms." in: Mutation research, Vol. 715, Issue 1-2, pp. 32-41, (2011) (PubMed).
: "Cells expressing FLT3/ITD mutations exhibit elevated repair errors generated through alternative NHEJ pathways: implications for genomic instability and therapy." in: Blood, Vol. 116, Issue 24, pp. 5298-305, (2010) (PubMed).
: "DNA polymerase beta-dependent long patch base excision repair in living cells." in: DNA repair, Vol. 9, Issue 2, pp. 109-19, (2010) (PubMed).
: "Mitochondrial localization of PARP-1 requires interaction with mitofilin and is involved in the maintenance of mitochondrial DNA integrity." in: The Journal of biological chemistry, Vol. 284, Issue 46, pp. 31616-24, (2009) (PubMed).
Aliases for LIG3 抗体
DNA ligase III (orf36) 抗体BRCT domain-containing protein (lig3) 抗体
DNA ligase 3 (LIG3) 抗体
ligase III, DNA, ATP-dependent (lig3) 抗体
DNA ligase 3 (Lig3) 抗体
DNA ligase III (Bm1_22840) 抗体
ligase III, DNA, ATP-dependent (Lig3) 抗体
DNA ligase 3 (ANI_1_2644024) 抗体
DNA ligase 3 (AOR_1_1174154) 抗体
DNA ligase 3 (LOC100634887) 抗体
ligase III, DNA, ATP-dependent L homeolog (lig3.L) 抗体
An02g06890 抗体
AO090003000668 抗体
D11Wsu78e 抗体
DDBDRAFT_0218523 抗体
DDBDRAFT_0232266 抗体
DDB_0218523 抗体
DDB_0232266 抗体
LIG2 抗体
LIG3 抗体
lig3 抗体
orf36 抗体
wu:fb12c02 抗体
wu:fd10b03 抗体
wu:fm79b09 抗体
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