Leptin 抗体
(Leptin (LEP))
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Jul 2008].
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Latest Publications for our Leptin 抗体
: "The A3 adenosine receptor agonist, namodenoson, ameliorates non‑alcoholic steatohepatitis in mice." in: International journal of molecular medicine, Vol. 44, Issue 6, pp. 2256-2264, (2019) (PubMed).: "lncRNA Ftx promotes aerobic glycolysis and tumor progression through the PPARγ pathway in hepatocellular carcinoma." in: International journal of oncology, Vol. 53, Issue 2, pp. 551-566, (2018) (PubMed).
: "MicroRNA-126 participates in lipid metabolism in mammary epithelial cells." in: Molecular and cellular endocrinology, Vol. 454, pp. 77-86, (2017) (PubMed).
: "Different expression of leptin and IGF1 in the adult and prepubertal testis in dogs." in: Reproduction in domestic animals = Zuchthygiene, Vol. 52 Suppl 2, pp. 187-192, (2017) (PubMed).
: "A Triterpenoid Inhibited Hormone-Induced Adipocyte Differentiation and Alleviated Dexamethasone-Induced Insulin Resistance in 3T3-L1 adipocytes." in: Natural products and bioprospecting, Vol. 5, Issue 3, pp. 159-66, (2015) (PubMed).
: "Correlation analysis between the expressions of leptin and its receptor (ObR) and clinicopathology in endometrial cancer." in: Cancer biomarkers : section A of Disease markers, Vol. 14, Issue 5, pp. 353-9, (2015) (PubMed).
: "Endotrophin triggers adipose tissue fibrosis and metabolic dysfunction." in: Nature communications, Vol. 5, pp. 3485, (2014) (PubMed).
: "Leptin induces cell proliferation and reduces cell apoptosis by activating c-myc in cervical cancer." in: Oncology reports, Vol. 29, Issue 6, pp. 2291-6, (2013) (PubMed).
: "Testis dysfunction by isoproterenol is mediated by upregulating endothelin receptor A, leptin and protein kinase Cvarepsilon and is attenuated by an endothelin receptor antagonist CPU0213." in: Reproductive toxicology (Elmsford, N.Y.), Vol. 29, Issue 4, pp. 421-6, (2010) (PubMed).
: "Genetics of leptin and obesity: a HuGE review." in: American journal of epidemiology, Vol. 162, Issue 2, pp. 101-14, (2005) (PubMed).
Aliases for Leptin 抗体
leptin (Lep) 抗体leptin (LEP) 抗体
leptin (lep) 抗体
LEPD 抗体
ob 抗体
OB 抗体
obese 抗体
OBS 抗体
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