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Low Density Lipoprotein Receptor 抗体

(Low Density Lipoprotein Receptor (LDLR))
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010].

101 results

LDLR 适用: 人, 小鼠, 大鼠, Hamster, 植物 WB, FACS, IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 680
产品编号 ABIN5006121
 
LDLR 适用: 人, 小鼠, 大鼠, Hamster, 植物 WB, FACS, IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 594
产品编号 ABIN2803735
 
LDLR 适用: 人, 小鼠, 大鼠, Hamster, 植物 WB, FACS, IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 555
产品编号 ABIN904681
 
LDLR 适用: 人, 小鼠, 大鼠, Hamster, 植物 WB, FACS, IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 488
产品编号 ABIN904682
 
LDLR 适用: 人, 小鼠, 大鼠, Hamster, 植物 WB, FACS, IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 647
产品编号 ABIN904683
 
LDLR 适用: 人, 小鼠, 大鼠, Hamster, 植物 WB, FACS, IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 350
产品编号 ABIN904680
 
LDLR 适用: 人, 小鼠, 大鼠, Hamster, 植物 WB, FACS, IF (p) 宿主: 兔 Polyclonal Cy7
产品编号 ABIN672117
 
LDLR 适用: 人, 小鼠, 大鼠, Hamster, 植物 WB, FACS, IF (p) 宿主: 兔 Polyclonal FITC
产品编号 ABIN672118
 
LDLR 适用: 人, 小鼠, 大鼠, Hamster, 植物 WB, FACS, IF (p) 宿主: 兔 Polyclonal Cy5.5
产品编号 ABIN672116
 
LDLR 适用: 人, 小鼠, 大鼠, Hamster, 植物 WB, FACS, IF (p) 宿主: 兔 Polyclonal Cy3
产品编号 ABIN672114
 
LDLR 适用: 人, 小鼠, 大鼠, Hamster, 植物 WB, FACS, IF (p) 宿主: 兔 Polyclonal Cy5
产品编号 ABIN672115
 
LDLR 适用: 人, 小鼠, 大鼠, Hamster, 植物 WB, FACS 宿主: 兔 Polyclonal PE
产品编号 ABIN6988160
 
LDLR 适用: 人, 小鼠 WB, IHC, FACS, IHC (p), IF (cc) 宿主: 兔 Monoclonal 1A7 unconjugated
产品编号 ABIN6943913
 
LDLR 适用: 人, 小鼠, 大鼠, Hamster, 植物 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN672113
 
LDLR 适用: 人, 小鼠, 大鼠, Hamster, 植物 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal HRP
产品编号 ABIN672120
 
LDLR 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7158566
 
LDLR 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7158565
 
LDLR 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7158564
 
LDLR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7642271
 
LDLR 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7642273
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • Flow Cytometry (FACS)
    • Immunohistochemistry (IHC)
    • ELISA
    • Immunoprecipitation (IP)
    • Immunocytochemistry (ICC)
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunofluorescence (IF)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunochromatography (IC)
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Immunofluorescence (fixed cells) (IF/ICC)
    • Inhibition (Inh)
    • Enzyme Immunoassay (EIA)
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Ligand Binding Assay (LBA)
    • Phage Display (PhD)
  • 适用
    • Human
    • Mouse
    • Rat
    • Hamster
    • Plant
    • Cow
    • Dog
    • Guinea Pig
    • Monkey
    • Pig
    • Rabbit
    • Horse
  • 论文引用
  • 图像
  • Preservative free only
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
    • Chicken
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
    • Chimeric
  • 克隆
    • 2B10
    • C7
    • IgG-C7
    • 11C32
    • 1A7
    • 1B10H10
    • 5E7
    • BFC-12
    • M5100921
    • MM0609-11A2
    • RB22886
  • 抗原表位
    • AA 781-860
    • Extracellular Domain
    • AA 391-419
    • AA 49-244
    • AA 497-742
    • AA 22-788
    • AA 29-205
    • AA 500-550
    • C-Term
    • AA 1-860
    • AA 105-205
    • AA 184-195
    • AA 22-150
    • AA 263-509
    • AA 335-588
    • AA 499-511
    • AA 184-196
    • AA 193-788
    • AA 25-186
    • AA 35-843
    • AA 451-500
    • AA 490-540
    • AA 540-620
    • AA 705-860
    • AA 810-860
    • Center
    • Internal Region
    • N-Term
  • 标记
    • 非结合性
    • Biotin
    • FITC
    • PE
    • APC
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • HRP
    • AbBy Fluor® 350
    • AbBy Fluor® 488
    • AbBy Fluor® 555
    • AbBy Fluor® 594
    • AbBy Fluor® 647
    • AbBy Fluor® 680
    • AbBy Fluor® 750
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
  • 抗体亚型
    • IgG
    • IgG1
    • IgG2b kappa
    • IgY
    • Ig Fraction
    • IgG2a
    • IgG kappa
  • 蛋白类型
    • Recombinant Antibody
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • KO Validated
  • Supplier
    • antibodies-online
    • Signalway
    • Biomatik
    • USBio
    • Abbexa
    • Acris
    • Boster Bio
    • PROGEN
    • Abcepta
    • Abiocode
    • Angio-Proteomie
    • Aviva Systems Biology
    • Cloud-Clone
    • Covalab
    • NSJ Bioreagents
    • Neuromics Antibodies
    • ProSci

Latest Publications for our Low Density Lipoprotein Receptor 抗体

Moessinger, Nilsson, Muhl, Zeitelhofer, Heller Sahlgren, Skogsberg, Eriksson: "VEGF-B signaling impairs endothelial glucose transcytosis by decreasing membrane cholesterol content." in: EMBO reports, Vol. 21, Issue 7, pp. e49343, (2020) (PubMed).

Lebeau, Platko, Al-Hashimi, Byun, Lhoták, Holzapfel, Gyulay, Igdoura, Cool, Trigatti, Seidah, Austin: "Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained." in: The Journal of biological chemistry, Vol. 293, Issue 19, pp. 7329-7343, (2019) (PubMed).

Khoshnejad, Patel, Wojtak, Kudchodkar, Humeau, Lyssenko, Rader, Muthumani, Weiner: "Development of Novel DNA-Encoded PCSK9 Monoclonal Antibodies as Lipid-Lowering Therapeutics." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 27, Issue 1, pp. 188-199, (2019) (PubMed).

Sharma, Gupta, Dahiya, Kumar, Vaiphei, Agnihotri: "Clinical relevance of cholesterol homeostasis genes in colorectal cancer." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 10, pp. 1314-1327, (2019) (PubMed).

Silva, Lütjohann, Hamid, Velasquez, Kerner, Larrazabal, Failing, Hermosilla, Taubert: "Besnoitia besnoiti infection alters both endogenous cholesterol de novo synthesis and exogenous LDL uptake in host endothelial cells." in: Scientific reports, Vol. 9, Issue 1, pp. 6650, (2019) (PubMed).

Xu, Xu, Xu, Yin, Zhang: "Global inactivation of carboxylesterase 1 (Ces1/Ces1g) protects against atherosclerosis in Ldlr-/-mice." in: Scientific reports, Vol. 7, Issue 1, pp. 17845, (2018) (PubMed).

Fischer, Albers, Krott, Hoffzimmer, Heine, Schmale, Scheja, Gordts, Heeren: "The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins." in: Molecular metabolism, Vol. 16, pp. 88-99, (2018) (PubMed).

Riad, Zeng, Weng, Winters, Xu, Makvandi, Metz, Carlin, Mach: "Sigma-2 Receptor/TMEM97 and PGRMC-1 Increase the Rate of Internalization of LDL by LDL Receptor through the Formation of a Ternary Complex." in: Scientific reports, Vol. 8, Issue 1, pp. 16845, (2018) (PubMed).

Saxena, Kaur, Chandra: "Differential Response of B Cells to an Immunogen, a Mitogen and a Chemical Carcinogen in a Mouse Model System" in: Asian Pacific journal of cancer prevention : APJCP, Vol. 19, Issue 1, pp. 81-90, (2018) (PubMed).

Sirois, Chrétien, Mbikay: "Comparing expression and activity of PCSK9 in SPRET/EiJ and C57BL/6J mouse strains shows lack of correlation with plasma cholesterol." in: Molecular genetics and metabolism reports, Vol. 10, pp. 11-17, (2017) (PubMed).

Aliases for Low Density Lipoprotein Receptor 抗体

low density lipoprotein receptor (LDLR) 抗体
low density lipoprotein receptor (Ldlr) 抗体
low density lipoprotein receptor a (ldlra) 抗体
low density lipoprotein receptor S homeolog (ldlr.S) 抗体
low density lipoprotein receptor L homeolog (ldlr.L) 抗体
FH 抗体
FHC 抗体
fhc 抗体
Hlb301 抗体
LDLA 抗体
LDLCQ2 抗体
ldlcq2 抗体
ldlr 抗体
ldlr-a 抗体
ldlr-b 抗体
ldlr2-a 抗体
LDLRA 抗体
LDL receptor-2 抗体
LDL receptor 1 抗体
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