LBP 蛋白
(Lipopolysaccharide Binding Protein (LBP))
The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). [provided by RefSeq, Apr 2012].
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Latest Publications for our LBP 蛋白
: "Necro-inflammatory response of pancreatic acinar cells in the pathogenesis of acute alcoholic pancreatitis." in: Cell death & disease, Vol. 4, pp. e816, (2013) (PubMed).: "A role for Toll-like receptor mediated signals in neutrophils in the pathogenesis of the anti-phospholipid syndrome." in: PLoS ONE, Vol. 7, Issue 7, pp. e42176, (2012) (PubMed).
: "Induction of a microbicidal protein psoriasin (S100A7), and its stimulatory effects on normal human keratinocytes." in: Journal of dermatological science, Vol. 52, Issue 3, pp. 216-9, (2008) (PubMed).
Aliases for LBP 蛋白
lipopolysaccharide binding protein (LBP) 蛋白lipopolysaccharide binding protein (Lbp) 蛋白
lipopolysaccharide-binding protein (LOC100472839) 蛋白
BPIFD2 蛋白
Bpifd2 蛋白
LBP 蛋白
LPSBP 蛋白
Ly88 蛋白
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