The protein encoded by this gene is a member of the immunoglobulin superfamily. It was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily, including LAIR1. The function of this protein is unknown, although it is thought to be secreted and may help modulate mucosal tolerance. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Lebbink, van den Berg, de Ruiter, Raynal, van Roon, Lenting, Jin, Meyaard: "The soluble leukocyte-associated Ig-like receptor (LAIR)-2 antagonizes the collagen/LAIR-1 inhibitory immune interaction." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 3, pp. 1662-9, (2008) (PubMed).
Aliases for LAIR2 抗体
leukocyte associated immunoglobulin like receptor 2 (LAIR2) 抗体 CD306 抗体