KLF1 抗体
(Kruppel-Like Factor 1 (erythroid) (KLF1))
This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009].
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Latest Publications for our KLF1 抗体
: "Transcriptional activity of erythroid Kruppel-like factor (EKLF/KLF1) modulated by PIAS3 (protein inhibitor of activated STAT3)." in: The Journal of biological chemistry, Vol. 290, Issue 15, pp. 9929-40, (2015) (PubMed).: "TET-mediated oxidation of methylcytosine causes TDG or NEIL glycosylase dependent gene reactivation." in: Nucleic acids research, Vol. 42, Issue 13, pp. 8592-604, (2014) (PubMed).
: "Garlic accelerates red blood cell turnover and splenic erythropoietic gene expression in mice: evidence for erythropoietin-independent erythropoiesis." in: PLoS ONE, Vol. 5, Issue 12, pp. e15358, (2011) (PubMed).
: "Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding." in: The Journal of biological chemistry, Vol. 286, Issue 28, pp. 24819-27, (2011) (PubMed).
: "KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching." in: Nature genetics, Vol. 42, Issue 9, pp. 742-4, (2010) (PubMed).
: "EKLF directly activates the p21WAF1/CIP1 gene by proximal promoter and novel intronic regulatory regions during erythroid differentiation." in: Molecular and cellular biology, Vol. 30, Issue 11, pp. 2811-22, (2010) (PubMed).
: "Krüppel-like transcription factor 4 contributes to maintenance of telomerase activity in stem cells." in: Stem cells (Dayton, Ohio), Vol. 28, Issue 9, pp. 1510-7, (2010) (PubMed).
: "Distinct modes of gene regulation by a cell-specific transcriptional activator." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 11, pp. 4213-8, (2009) (PubMed).
: "CTCF-dependent enhancer-blocking by alternative chromatin loop formation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 51, pp. 20398-403, (2008) (PubMed).
: "Basic residues within the Kruppel zinc finger DNA binding domains are the critical nuclear localization determinants of EKLF/KLF-1." in: The Journal of biological chemistry, Vol. 277, Issue 18, pp. 16304-12, (2002) (PubMed).
Aliases for KLF1 抗体
Kruppel-like factor 1 (erythroid) (KLF-4) 抗体Kruppel like factor 1 (KLF1) 抗体
Kruppel-like factor 1 (erythroid) (Klf1) 抗体
Kruppel like factor 1 (Klf1) 抗体
EKLF 抗体
Eklf 抗体
HBFQTL6 抗体
INLU 抗体
KLF1 抗体
Nan 抗体
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