HAV IgM ELISA 试剂盒
This Hepatitis A Virus (HAV) HAV IgM ELISA Kit is a Colorimetric ELISA Kit designed to quantify Hepatitis A Virus (HAV) HAV IgM.
Quick Overview for HAV IgM ELISA 试剂盒 (ABIN997031)
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HAV IgM
(Anti-Hepatitis A Virus Antibody IgM (HAV IgM))
适用
Hepatitis A Virus (HAV)
检测方法
Colorimetric
实验类型
Competition ELISA
应用范围
ELISA
样品类型
Serum
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原理
- The HAV IgM ELISA test is an enzyme-linked immunosorbent assay (ELISA) which is used for the qualitative determination of IgM-class antibodies to hepatitis A virus in human serum/plasma.
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Analytical Method
- Qualitative
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特异性
- 100%
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灵敏度
- 100%
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样本量
- 100 μL
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实验时间
- 1 - 2 h
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板类型
- Pre-coated
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限制
- 仅限研究用
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储存条件
- 4 °C
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有效期
- 12-18 months
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- HAV IgM (Anti-Hepatitis A Virus Antibody IgM (HAV IgM))
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别名
- HAV IgM
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物质类
- Antibody
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背景
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Hepatitis A is a self-limited disease and chronic stage or other complications are rare. Infections occur early in life in areas where sanitation is poor and living conditions are crowded. With improved sanitation and hygiene, infections are delayed and consequently the number of persons susceptible to the disease increases. Because the disease is transmitted through the fecal-oral route in dense populated regions, an outbreak can arise from single contaminated source. The cause of hepatitis A is hepatitis A virus (HAV)-non enveloped positive strand RNA virus with a linear single strand genome, encoding for only one known serotype.
HAV has four major, structural polypeptides and it localizes exclusively in the cytoplasm of human hepatocytes. The infection with HAV induces strong immunological response and elevated levels first of IgM and then IgG are detectable within a few days after the onset of the symptoms. The presence of anti–HAV IgM is an important serological marker for early detection and observation of the clinical manifestation of the disease. Increasing levels of anti-HAV IgM are detectable about three weeks after exposure with highest titter after four to six weeks later. Within six months after infection IgM concentration declines to non-detectable levels.
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