HBsAb ELISA 试剂盒
This Hepatitis B Virus (HBV) HBsAb ELISA Kit is a Colorimetric ELISA Kit designed to quantify Hepatitis B Virus (HBV) HBsAb.
Quick Overview for HBsAb ELISA 试剂盒 (ABIN997016)
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HBsAb
(Anti-Hepatitis B Virus Surface Antibody (HBsAb))
适用
Hepatitis B Virus (HBV)
检测方法
Colorimetric
实验类型
Sandwich ELISA
应用范围
ELISA
样品类型
Serum
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原理
- HBsAb ELISA Test is an enzyme linked immunosorbent assay (ELISA) for in vitro qualitative detection of antibodies to hepatitis B virus surface antigen (anti-HBs) in human serum or plasma.
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Analytical Method
- Qualitative
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特异性
- 99.70%
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灵敏度
- 100%
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样本量
- 50 μL
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实验时间
- 1 - 2 h
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板类型
- Pre-coated
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限制
- 仅限研究用
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储存条件
- 4 °C
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有效期
- 12-18 months
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- HBsAb (Anti-Hepatitis B Virus Surface Antibody (HBsAb))
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别名
- HbsAb
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物质类
- Antibody, Antibody
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背景
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Hepatitis B virus (HBV) is an enveloped, double-stranded DNA virus belonging to the Hepadnaviridae family and is recognized as the major cause of blood transmitted hepatitis together with hepatitis C virus (HCV). Infection with HBV induces a spectrum of clinical manifestations ranging from mild, inapparent disease to fulminant hepatitis, severe chronic liver disease, which in some cases can lead to cirrhosis and carcinoma of the liver. Classification of a hepatitis B infection requires the identification of several serological markers expressed during three phases (incubation, acute and convalescent) of the infection. Now several diagnostic tests are used for screening, clinical diagnosis and management of the disease. Hepatitis B surface antigen (HBsAg), which appears shortly after infection is an important protein of the envelope structure of the virus.
HBsAg is a key serological marker for detection and diagnosis of HBV and is detectable in blood during the acute phase of the disease. Clearance after treatment shows recovery while presence for more than half year after infection indicates possible progression to long chronic carrier stage. During the acute phase of the infection, strong immunological response develops and increasing titers of HBsAg neutralizing antibodies (anti-HBs) are marker for recovery. The serological detection of anti-HBs has become important method for the follow up of patients infected by HBV, prospective prevalence studies, and the monitoring of recipients upon vaccination with synthetic and natural HBsAg based vaccines.
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