MUC1 ELISA 试剂盒
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Quick Overview for MUC1 ELISA 试剂盒 (ABIN996900)
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See all MUC1 ELISA试剂盒检测方法
实验类型
检测范围
应用范围
样品类型
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最低检测浓度
- 0 U/mL
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原理
- Enzyme Immunoassay for the Quantitative Measurement of Breast Cancer Antigen (CA15-3) in Human Serum.
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Analytical Method
- Quantitative
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特异性
- 97 %
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灵敏度
- 5 U/mL
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Mucin 1 (MUC1) ELISA Kit
MUC1 适用: 人 Colorimetric Sandwich ELISA 0.62 ng/mL - 40 ng/mL Cell Culture Supernatant, Cell Lysate, Tissue Homogenate
Mucin 1 (MUC1) ELISA KitMUC1 适用: 大鼠 Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Saliva, Serum, Tissue Homogenate
Mucin 1 (MUC1) ELISA KitMUC1 适用: 小鼠 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Culture Supernatant, Cell Lysate, Tissue Homogenate
Mucin 1 (MUC1) ELISA KitMUC1 适用: 小鼠 Colorimetric Sandwich ELISA 78.125 pg/mL - 5000 pg/mL Plasma, Serum, Tissue Homogenate
Mucin 1 (MUC1) ELISA KitMUC1 适用: 人 Colorimetric Sandwich ELISA 15.625 pg/mL - 1000 pg/mL Biological Fluids, Plasma, Serum, Tissue Homogenate
Mucin 1 (MUC1) ELISA KitMUC1 适用: 兔 Colorimetric Competition ELISA 50-800 IU/mL Plasma, Serum, Tissue Homogenate
Mucin 1 (MUC1) ELISA KitMUC1 适用: 人 Colorimetric Competition ELISA 0.5-10 ng/mL Cell Culture Supernatant, Plasma, Serum, Tissue Homogenate
Mucin 1 (MUC1) ELISA KitMUC1 适用: Cow Colorimetric Sandwich ELISA 0.312 ng/mL - 20 ng/mL Cell Lysate, Tissue Homogenate
Mucin 1 (MUC1) ELISA KitMUC1 适用: 犬 Colorimetric Competition ELISA 50-1000 IU/mL Cell Culture Supernatant, Plasma, Serum, Tissue Homogenate
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样本量
- 20 μL
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实验时间
- 2 - 3 h
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板类型
- Pre-coated
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限制
- 仅限研究用
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储存条件
- 4 °C
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有效期
- 12-14 months
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- MUC1 (Mucin 1 (MUC1))
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别名
- CA15-3
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背景
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Breast cancer is the most common life-threatening malignant lesion in women of many developed countries today, with approximately 180,000 new cases diagnosed every year. Roughly half of these newly diagnosed patients are node-negative, however 30% of these cases progress to metastatic disease. here are a number of tumor markers that can help clinicians to identify and diagnose which breast cancer patients will have aggressive disease and which will have an indolent course. These markers include estrogen and progesterone receptors, DNA ploidy and percent-S phase profile, epidermal growth factor receptor, HER-2/neu oncogene, p53 tumor suppressor gene, cathepsin D, proliferation markers and CA15-3.
CA15-3 is most useful for monitoring patients post-operatively for recurrence, particularly metastatic diseases. 96% of patients with local and systemic recurrence have elevated CA15-3, which can be used to predict recurrence earlier than radiological and clinical criteria. A 25% increase in the serum CA15-3 is associated with progression of carcinoma. A 50% decrease in serum CA15-3 is associated with response to treatment. CA15-3 are more sensitive than CEA in early detection of breast cancer recurrence. In combination with CA-125, CA15-3 has been shown to be useful in early detection of relapse of ovarian cancer. CA15-3 levels are also increased in colon, lung and hepatic tumors. -
途径
- Negative Regulation of intrinsic apoptotic Signaling
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