Anti-Parietal Cell ELISA 试剂盒
This 人 ELISA Kit is a Colorimetric ELISA Kit designed to quantify 人 .
Quick Overview for Anti-Parietal Cell ELISA 试剂盒 (ABIN930717)
抗原
Anti-Parietal Cell
适用
人
检测方法
Colorimetric
实验类型
Sandwich ELISA
应用范围
ELISA
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Analytical Method
- Quantitative
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产品特性
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ELISA kit for the detection of Parietal Cell in the research laboratory
Alternative Names: Parietal cell ELISA kit -
纯化方法
- Ascites, ammnonium sulphate purified
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应用备注
- Optimal conditions to be determined by end-user
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板类型
- Pre-coated
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实验流程
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AntiParietal Cell (H+/K+ATPase) is an indirect solid phase enzyme immunometric assay (ELISA). It is designed for the quantitative measurement of IgG class autoantibodies directed against the a and bsubunits of the Parietal Cell H+/K+ATPase. Preparations of highly purified pig Parietal Cell H+/K+ATPase are coated on microplates. The microplates can be divided into 12 modules of 8 wells each or can be used completely for 96 determinations. Each well can be separated from the module (
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限制
- 仅限研究用
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储存条件
- 4 °C
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储存方法
- Store at 2-8 °C.
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- Anti-Parietal Cell
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物质类
- Antibody
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背景
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Autoantibodies against the H/K ATPase can be detected in 80-90 % of pernicious anemia patients, by indirect immunofluorescence and they are also detected in 20 % of the healthy adult population. ELISA test systems show a sensitivity of about 80 % and specificity of about 90 %. There is an age related increase in the presence of parietal cell autoantibodies in the adult population. A study of the relationship between parietal cell autoantibody and gastric mucosal morphology, indicates these parietal cell positive individuals in a random population may indeed have early type A gastritis. Higher prevalence rates (20-30 %) of parietal cell autoantibodies have been noted in patients with autoimmune endocrine disorders such as thyrotoxicosis, Hashimoto's thyroiditis and insulin-dependent diabetes. Histological examinations of gastric biopsies reveals that the majority of parietal cell autoantibody positive individuals also have a type A gastric lesion.
Synonyms: Parietal cell ELISA kit.
抗原
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