Anti-Parietal Cell ELISA 试剂盒
适用: 人
Colorimetric
Sandwich ELISA
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- 抗原
- Anti-Parietal Cell
- 适用
- 人
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 应用范围
- ELISA
- Analytical Method
- Quantitative
- 产品特性
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ELISA kit for the detection of Parietal Cell in the research laboratory
Alternative Names: Parietal cell ELISA kit - 纯化方法
- Ascites, ammnonium sulphate purified
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- 应用备注
- Optimal conditions to be determined by end-user
- 板类型
- Pre-coated
- 实验流程
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AntiParietal Cell (H+/K+ATPase) is an indirect solid phase enzyme immunometric assay (ELISA). It is designed for the quantitative measurement of IgG class autoantibodies directed against the a and bsubunits of the Parietal Cell H+/K+ATPase. Preparations of highly purified pig Parietal Cell H+/K+ATPase are coated on microplates. The microplates can be divided into 12 modules of 8 wells each or can be used completely for 96 determinations. Each well can be separated from the module (
- 限制
- 仅限研究用
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- 储存条件
- 4 °C
- 储存方法
- Store at 2-8 °C.
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- 抗原
- Anti-Parietal Cell
- 物质类
- Antibody
- 背景
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Autoantibodies against the H/K ATPase can be detected in 80-90 % of pernicious anemia patients, by indirect immunofluorescence and they are also detected in 20 % of the healthy adult population. ELISA test systems show a sensitivity of about 80 % and specificity of about 90 %. There is an age related increase in the presence of parietal cell autoantibodies in the adult population. A study of the relationship between parietal cell autoantibody and gastric mucosal morphology, indicates these parietal cell positive individuals in a random population may indeed have early type A gastritis. Higher prevalence rates (20-30 %) of parietal cell autoantibodies have been noted in patients with autoimmune endocrine disorders such as thyrotoxicosis, Hashimoto's thyroiditis and insulin-dependent diabetes. Histological examinations of gastric biopsies reveals that the majority of parietal cell autoantibody positive individuals also have a type A gastric lesion.
Synonyms: Parietal cell ELISA kit.
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