MYH11
(Myosin Heavy Chain 11, Smooth Muscle (MYH11))
别名
Sm1
背景
Today the best investigated immunoreactive antigens are double stranded DNA (dsDNA), single stranded DNA, snRNP (small nuclear ribonucleoprotein particles), the complex RNP/Sm which is stabilized by ribonuleic acid as well as SSA (Ro) and SSB (La). Smith Antigen (Sm) is an autoantigen on a series of particles composed of RNA and protein. Unlike RNP, the sm antigen is resistant to RNase, but partially sensitive to trypsin. It is involved in the pathogenesis of Systemic lupus erythematosus (SLE). Synonyms: Smith antigen ELISA kit.