LGALS3BP ELISA 试剂盒
Quick Overview for LGALS3BP ELISA 试剂盒 (ABIN930449)
抗原
See all LGALS3BP ELISA试剂盒适用
检测方法
实验类型
应用范围
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Analytical Method
- Quantitative
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产品特性
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ELISA kit for the detection of Mac2 BP in the research laboratory
Alternative Names: Mac2BP ELISA kit, Mac-2-Binding Protein ELISA kit, L3 antigen ELISA kit, Basement membrane Autoantigen p105 ELISA kit, Serum protein 90K ELISA kit, M2BP ELISA kit
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Lectin, Galactoside-Binding, Soluble, 3 Binding Protein (LGALS3BP) ELISA Kit
LGALS3BP 适用: 人 Colorimetric Sandwich ELISA 1.56 ng/mL - 100 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Lectin, Galactoside-Binding, Soluble, 3 Binding Protein (LGALS3BP) ELISA KitLGALS3BP 适用: 小鼠 Colorimetric Sandwich ELISA 0.39 ng/mL - 25 ng/mL Plasma, Serum, Tissue Homogenate
Lectin, Galactoside-Binding, Soluble, 3 Binding Protein (LGALS3BP) ELISA KitLGALS3BP 适用: 小鼠 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Plasma, Serum
Lectin, Galactoside-Binding, Soluble, 3 Binding Protein (LGALS3BP) ELISA KitLGALS3BP 适用: 大鼠 Colorimetric Sandwich ELISA 1.56 ng/mL - 100 ng/mL Plasma, Serum, Tissue Homogenate
Lectin, Galactoside-Binding, Soluble, 3 Binding Protein (LGALS3BP) ELISA KitLGALS3BP 适用: 人 AA 19-585 Colorimetric Sandwich ELISA 62.5-4000 pg/mL Cell Culture Supernatant, Plasma (heparin), Serum
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应用备注
- Optimal conditions to be determined by end-user
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板类型
- Pre-coated
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实验流程
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An anti90K/Mac2 BP monoclonal coating antibody is adsorbed onto microwells. 90K/Mac2 BP present in the sample orstandard binds to the antibody adsorbed to the microwells. Following incubation a HRPconjugated monoclonal anti90K/Mac2 BP antibody is added and binds to 90K/Mac2 BP captured by the first antibody. Unbound enzyme conjugated anti90K/Mac2 BP is removed during a wash step and substrate solution reactive with HRP is added to the wells. A coloured product is formed in proportion to the amount of soluble 90K/Mac2 BP present in the sample. The reaction is terminated by addition of acid and absorbance is measured at 450nm. A standard curve is prepared from five 90K/Mac2 BP standards and 90K/Mac2 BP sample concentration determined.
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限制
- 仅限研究用
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储存条件
- 4 °C
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储存方法
- Store at 2-8 °C.
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- LGALS3BP (Lectin, Galactoside-Binding, Soluble, 3 Binding Protein (LGALS3BP))
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别名
- Mac2BP
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背景
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90K/Mac2 BP is a widely expressed secreted 90 kDa human serum glycoprotein, originally identified in the supernatant of human breast cancer cells. It is identical to Mac2 BP, the ligand for the secreted lactose/galactose specific S-lectin Mac2 which is highly expressed by cells of the macrophage/monocyte lineage as well as a variety of other cell types. Although the biological functions and possible roles of 90K/Mac2 BP are largely unknown, some evidence indicates a role in the immunitary defence mechanism. Serum levels of 90K/Mac2 BP have been determined in patients with various forms of neoplasia and in some viral infections. In breast and colorectal cancer and in non-Hodgkin lymphoma, high levels of 90K/Mac2 BP are correlated with a poor prognosis. In HIV infection, high serum concentrations of 90K/Mac2 BP may serve as a predictor of faster progression to AIDS, independently of the numbers of CD4+ lymphocytes. In a series of HCV-infected patients, a correlation was found between elevated serum levels of 90K/Mac2 BP and failure to respond to treatment with alpha interferon. The determination of 90K/Mac2 BP in the serum can therefore be used as a valuable parameter for monitoring the outcome of cancer and viral infections.
Synonyms: Mac2BP ELISA kit, Mac-2-Binding Protein ELISA kit, L3 antigen ELISA kit, Basement membrane Autoantigen p105 ELISA kit, Serum protein 90K ELISA kit, M2BP ELISA kit.
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