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Neuropilin 1 ELISA 试剂盒

NRP1 适用: 大鼠 Colorimetric Sandwich ELISA 780 pg/mL - 50000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
产品编号 ABIN6720264
发货至: 中国
  • 抗原 See all Neuropilin 1 (NRP1) ELISA试剂盒
    Neuropilin 1 (NRP1)
    适用
    • 5
    • 5
    • 3
    • 1
    大鼠
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    检测范围
    780 pg/mL - 50000 pg/mL
    最低检测浓度
    780 pg/mL
    应用范围
    ELISA
    原理
    Sandwich ELISA for Quantitative Detection of Antigen
    样品类型
    Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
    Analytical Method
    Quantitative
    产品特性

    Synonyms: A5 protein, BDCA4, BLOOD DENDRITIC CELL ANTIGEN 4, CD 304, CD304, DKFZp686A03134, DKFZp781F1414, Neuropilin-1, Neuropilin1, Neuropilin1 transmembrane receptor, NP1, NPN1, NRP 1, NRP, NRP1, NRP1_HUMAN, Vascular endothelial cell growth factor 165 receptor, VEGF165R

    Background: NRP1(Neuropilin 1) also known as NP1, NRP, BDCA4 or VEGF165R, is a membrane-bound coreceptor to a tyrosine kinase receptor for both vascular endothelial growth factor (VEGF) and semaphorin family members. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion. By somatic cell hybrid analysis, the NRP1 gene was mapped to chromosome 10. NRP1 bounds PGF1 with lower affinity. NRP1-mediated interactions are a necessary element in the initiation of the primary immune response and offer another example, like that of agrin, of a molecule shared by neurologic and immunologic synapses. After T-cell contact with DC, T-cell NRP1 colocalized with CD3 in the immunologic synapse and, sometimes, also at the opposite pole of the T cell. Soluble NRP1 interacts in a homophilic fashion with NRP1 on both DC and T cells, and this binding can be inhibited by blocking antibodies to NRP1. Furthermore, selective NRP1 inhibition in this model suppressed neovascular formation substantially.

    Gene Name: NRP1

    Production: Natural and recombinant rat Neuropilin-1. There is no detectable cross-reactivity with other relevant proteins.

    Standard: Expression system for standard: NSO, Immunogen sequence: F22-D854

    Top Product
    Discover our top product NRP1 ELISA Kit
  • 应用备注

    Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 50 ng/mL, 25 ng/mL, 12.5 ng/mL, 6.25 ng/mL, 3.12 ng/mL, 1.56 ng/mL, 0.78 ng/mL rat Neuropilin-1 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of rat cell culture supernates, serum or plasma(heparin, EDTA) to each empty well. We recommend that each rat Neuropilin-1 standard solution and each sample is measured in duplicate.

    Blood Product Anticoagulant: Heparin Sodium

    ELISA Dilution: 780pg/mL-50,000pg/mL

    样本量
    100 μL
    板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    RT,4 °C,-20 °C
    储存方法
    Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
  • 抗原 See all Neuropilin 1 (NRP1) ELISA试剂盒
    Neuropilin 1 (NRP1)
    别名
    Neuropilin-1 (NRP1 产品)
    别名
    NRP1 ELISA Kit, cd304 ELISA Kit, neuropilin ELISA Kit, np-1 ELISA Kit, npn-1 ELISA Kit, nrp ELISA Kit, nrp-1 ELISA Kit, vegf165r ELISA Kit, BDCA4 ELISA Kit, CD304 ELISA Kit, NP1 ELISA Kit, NRP ELISA Kit, VEGF165R ELISA Kit, C530029I03 ELISA Kit, NP-1 ELISA Kit, NPN-1 ELISA Kit, Npn1 ELISA Kit, Nrp ELISA Kit, neuropilin 1 ELISA Kit, neuropilin 1 L homeolog ELISA Kit, NRP1 ELISA Kit, nrp1 ELISA Kit, Nrp1 ELISA Kit, nrp1.L ELISA Kit
    基因ID
    246331
    NCBI登录号
    NP_659566
    UniProt
    Q9QWJ9
    途径
    Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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