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Corin ELISA 试剂盒

CORIN 适用: 人 Colorimetric Sandwich ELISA 62.5 pg/mL - 4000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
产品编号 ABIN6720220
发货至: 中国
  • 抗原 See all Corin (CORIN) ELISA试剂盒
    Corin (CORIN) (Corin, Serine Peptidase (CORIN))
    适用
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    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    检测范围
    62.5 pg/mL - 4000 pg/mL
    最低检测浓度
    62.5 pg/mL
    应用范围
    ELISA
    原理
    Sandwich ELISA for Quantitative Detection of Antigen
    样品类型
    Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
    Analytical Method
    Quantitative
    产品特性

    Synonyms: activated protease fragment, ATC 2, ATC2, Atrial natriuretic peptide-converting enzyme, Atrial natriuteric peptide converting enzyme, Corin, Corin serine peptidase, CORIN_HUMAN, CRN, Heart specific serine proteinase, Heart specific serine proteinase ATC2, Heart-specific serine proteinase ATC2, Lrp 4, Lrp4, MGC119742, Pro ANP convertase, Pro ANP converting enzyme, Pro-ANP-converting enzyme, TMPRSS 10, TMPRSS10, Transmembrane protease serine 10

    Background: Atrial natriuretic peptide-converting enzyme, also called CRN or ATC2, is a protein that in humans is encoded by the CORIN gene. It is mapped to 4p12. This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. It has been found that Corin is the pro-ANP-converting enzyme and that Corin-mediated pro-ANP activation may play a role in regulating blood pressure. What's more, Corin and ANP are essential for physiologic changes at the maternal-fetal interface. This protein may also function as a pro-brain-type natriuretic peptide convertase. Corin gene mutations which cause Corin to impair activity might be an underlying mechanism in hypertension.

    Gene Name: CORIN

    Production: Natural and recombinant human Corin. There is no detectable cross-reactivity with other relevant proteins.

    Standard: Expression system for standard: NSO, Immunogen sequence: S67-N1042

    Top Product
    Discover our top product CORIN ELISA Kit
  • 应用备注

    Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 4000pg/mL, 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL human Corin standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum, plasma(heparin, EDTA) or tissue homogenates to each empty well. It is recommended that each human Corin standard solution and each sample be measured in duplicate.

    Blood Product Anticoagulant: Heparin Sodium

    ELISA Dilution: 62.5pg/mL-4000pg/mL

    样本量
    100 μL
    板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    RT,4 °C,-20 °C
    储存方法
    Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
  • 抗原 See all Corin (CORIN) ELISA试剂盒
    Corin (CORIN) (Corin, Serine Peptidase (CORIN))
    别名
    Corin (CORIN 产品)
    别名
    CORIN ELISA Kit, CG2105 ELISA Kit, Dmel\\CG2105 ELISA Kit, SP75 ELISA Kit, LOC559109 ELISA Kit, AV273130 ELISA Kit, Lrp4 ELISA Kit, ATC2 ELISA Kit, CRN ELISA Kit, PEE5 ELISA Kit, TMPRSS10 ELISA Kit, corin, serine peptidase ELISA Kit, CG2105 gene product from transcript CG2105-RC ELISA Kit, novel protein similar to H.sapiens CORIN, corin, serine peptidase (CORIN) ELISA Kit, corin ELISA Kit, CORIN ELISA Kit, Corin ELISA Kit, LOC559109 ELISA Kit
    基因ID
    10699
    NCBI登录号
    NP_001265514
    UniProt
    Q9Y5Q5
    途径
    Regulation of Systemic Arterial Blood Pressure by Hormones
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