Corin ELISA 试剂盒
Quick Overview for Corin ELISA 试剂盒 (ABIN6720220)
抗原
See all Corin (CORIN) ELISA试剂盒适用
检测方法
实验类型
检测范围
应用范围
样品类型
-
-
最低检测浓度
- 62.5 pg/mL
-
Supplier Product No.
- koa0759
-
Supplier
- Rockland
-
原理
- Human Corin Sandwich ELISA Kit for Quantitative Detection
-
品牌
- AccuSignal™
-
Analytical Method
- Quantitative
-
特异性
-
Production: Natural and recombinant human Corin. There is no detectable cross-reactivity with other relevant proteins.
-
灵敏度
- < 10 pg/mL
-
组件
-
- Antibody-coated 96-well plate
- Target Protein Standard
- Detection antibody
- Detection reagent
- Diluent buffers
- Wash buffers
- Substrate Solution
- Stop solutions
- Adhesive covers
-
-
Corin, Serine Peptidase (CORIN) ELISA Kit
CORIN 适用: 小鼠 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Plasma, Serum
Corin, Serine Peptidase (CORIN) ELISA KitCORIN 适用: 人 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate
Corin, Serine Peptidase (CORIN) ELISA KitCORIN 适用: 人 Colorimetric Sandwich ELISA 0.625 ng/mL - 40 ng/mL Cell Culture Supernatant, Plasma, Serum, Tissue Homogenate
Corin, Serine Peptidase (CORIN) ELISA KitCORIN 适用: 大鼠 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate
Corin, Serine Peptidase (CORIN) ELISA KitCORIN 适用: 人 AA 67-1042 Colorimetric Sandwich ELISA 62.5-4000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum, Tissue Homogenate
Corin, Serine Peptidase (CORIN) ELISA KitCORIN 适用: 人 Colorimetric Sandwich ELISA 63-4000 pg/mL Cell Lysate, Plasma, Serum
-
-
应用备注
- Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 4000pg/mL, 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL human Corin standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum, plasma(heparin, EDTA) or tissue homogenates to each empty well. It is recommended that each human Corin standard solution and each sample be measured in duplicate.
-
说明
-
Standard: Expression system for standard: NSO, Immunogen sequence: S67-N1042
-
样本量
- 100 μL
-
板类型
- Pre-coated
-
限制
- 仅限研究用
-
-
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
-
有效期
- 12 months
-
-
- Corin (CORIN) (Corin, Serine Peptidase (CORIN))
-
别名
- Corin
-
背景
-
Synonyms: activated protease fragment, ATC 2, ATC2, Atrial natriuretic peptide-converting enzyme, Atrial natriuteric peptide converting enzyme, Corin, Corin serine peptidase, CORIN_HUMAN, CRN, Heart specific serine proteinase, Heart specific serine proteinase ATC2, Heart-specific serine proteinase ATC2, Lrp 4, Lrp4, MGC119742, Pro ANP convertase, Pro ANP converting enzyme, Pro-ANP-converting enzyme, TMPRSS 10, TMPRSS10, Transmembrane protease serine 10
Background: Atrial natriuretic peptide-converting enzyme, also called CRN or ATC2, is a protein that in humans is encoded by the CORIN gene. It is mapped to 4p12. This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. It has been found that Corin is the pro-ANP-converting enzyme and that Corin-mediated pro-ANP activation may play a role in regulating blood pressure. What's more, Corin and ANP are essential for physiologic changes at the maternal-fetal interface. This protein may also function as a pro-brain-type natriuretic peptide convertase. Corin gene mutations which cause Corin to impair activity might be an underlying mechanism in hypertension.
-
基因ID
- 10699
-
NCBI登录号
- NP_001265514
-
UniProt
- Q9Y5Q5
-
途径
- Regulation of Systemic Arterial Blood Pressure by Hormones
抗原 See all Corin (CORIN) ELISA试剂盒
-
