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FSH ELISA 试剂盒

人 FSH ELISA Kit, Colorimetric is an assay for quantification of 人 FSH.
产品编号 ABIN577075
发货至: 中国
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Quick Overview for FSH ELISA 试剂盒 (ABIN577075)

抗原

See all FSH ELISA试剂盒
FSH (Follicle-Stimulating Hormone (FSH))

适用

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检测方法

Colorimetric

实验类型

Sandwich ELISA

应用范围

ELISA
  • 原理

    For the quantitative determination of human follicle stimulating hormone (FSH) concentrations in serum

    Analytical Method

    Quantitative

    灵敏度

    The minimal detectable concentration of FSH by this assay is estimated to be 1.5 mIU/mL.

    组件

    Standards: 1 set/2 vials
  • 板类型

    Pre-coated

    限制

    仅限研究用
  • 储存液

    Without preservative
  • 抗原 See all FSH ELISA试剂盒

    FSH (Follicle-Stimulating Hormone (FSH))

    别名

    Follicle Stimulating Hormone (FSH)

    物质类

    Hormone

    背景

    Epidermal growth factor (EGF), a polypeptide mitogen, was first observed in 1959 by Cohen and Levi-Montalcini while studying Nerve Growth Factor (NGF) in snake venom extracts.1 It was subsequently isolated and purified from mouse submandibular glands. When injected into new- born mice this new factor caused precocious eyelid opening and incisor eruption.2,3 EGF was further purified, based on its ability to induce the proliferation of basal skin cells.4 Also, a potent inhibitor of gastric acid secretion was identified and isolated from the urine of a pregnant women, and named human -urogastrone. It was shown that this protein was very similar to purified human EGF.5,6 The cDNA cloning of mature EGF revealed that this polypeptide (6 kDa, 53 amino acids) belonged to a family of growth factors (TGF- , vaccinia virus growth factor and amphiregulin) that bind to the same 16-185 kDa family of cell surface receptors. Structurally EGF is homologous to TGF- .7,8,9 Mature EGF is formed when the large precursor molecule (pre-EGF), a transmembrane protein (13 kDa, 1217 amino acids) which contains at least seven EGF-like sequences is cleaved. Within this precursor molecule, it is the sequence closest to the C-terminus of the mRNA that represents the coding region for the mature, soluble EGF sequence.7,1 The uncleaved precursor shows biological activity and is capable of binding to the EGF receptor.11,12 The physiological significance of the EGF precursor, nor the mechanisms of its processing into mature EGF have yet to be illustrated. However it is a source for soluble EGF and may be involved in cell to cell signalling or

    途径

    Peptide Hormone Metabolism, Chromatin Binding
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