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CRLF2 ELISA 试剂盒

CRLF2 适用: 小鼠 AA 20-233 Colorimetric Sandwich ELISA 125 pg/mL - 8000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
产品编号 ABIN5692222
发货至: 中国
  • 抗原 See all CRLF2 ELISA试剂盒
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    抗原表位
    AA 20-233
    适用
    • 4
    • 1
    小鼠
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    检测范围
    125 pg/mL - 8000 pg/mL
    最低检测浓度
    125 pg/mL
    应用范围
    ELISA
    原理
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse CRLF2. 96wells/kit, with removable strips.
    品牌
    PicoKine™
    样品类型
    Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
    Analytical Method
    Quantitative
    特异性
    Expression system for standard: NSO, Immunogen sequence: A20-L233
    灵敏度
    < 10 pg/mL
    组件
    96-well plate precoated with antibody
    lyophilized recombinant standard
    biotinylated antibody (dilution 1:100)
    Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
    Sample diluent buffer
    Antibody diluent buffer
    ABC diluent buffer
    TMB color developing agent
    TMB stop solution
    Adhesive cover
    Top Product
    Discover our top product CRLF2 ELISA Kit
  • 实验时间
    15 min
    板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    有效期
    12 months
  • 抗原 See all CRLF2 ELISA试剂盒
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    别名
    Crlf2 (CRLF2 产品)
    别名
    CRLF2 ELISA Kit, CRL2 ELISA Kit, CRLF2Y ELISA Kit, TSLPR ELISA Kit, CRLM2 ELISA Kit, Ly114 ELISA Kit, Tpte2 ELISA Kit, Tslpr ELISA Kit, Crl2 ELISA Kit, cytokine receptor like factor 2 ELISA Kit, cytokine receptor-like factor 2 ELISA Kit, CRLF2 ELISA Kit, Crlf2 ELISA Kit
    背景

    Synonyms: Cytokine receptor-like factor 2, Cytokine receptor-like molecule 2, CRLM-2, Thymic stromal lymphopoietin protein receptor, TSLP receptor, Type I cytokine receptor delta 1, Crlf2, Crlm2, Tpte2, Tslpr

    Tissue Specificity: High level of expression in liver, lung and testis. Also expressed in heart, brain, spleen, thymus and bone marrow. Highly expressed in progenitors and myeloid cells. Isoform 2 is expressed in primary hemotopoietic cells.

    Background: Cytokine receptor-like factor 2, also known as TSLPR or CRL2, is a protein that in humans is encoded by the CRLF2 gene. It is mapped to Xp22.33. The protein encoded by this gene is a receptor for thymic stromal lymphopoietin(TSLP). Together with the interleukin 7 receptor(IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Two transcript variants encoding different isoforms have been found for this gene. In addition to it, it has been found that rearrangement of CRLF2 and JAK mutation together contribute to leukemogenesis in B-progenitor ALL.

    Cellular Localisation: Isoform 1: Cell membrane, Single-pass type I membrane protein.
    UniProt
    Q8CII9
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