ENPP2 ELISA 试剂盒
Quick Overview for ENPP2 ELISA 试剂盒 (ABIN5692213)
抗原
See all ENPP2 ELISA试剂盒抗原表位
适用
检测方法
实验类型
检测范围
应用范围
样品类型
-
-
最低检测浓度
- 625 pg/mL
-
原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Autotaxin. 96wells/kit, with removable strips.
-
品牌
- PicoKine™
-
Analytical Method
- Quantitative
-
特异性
- Expression system for standard: NSO, Immunogen sequence: A36-I863
-
灵敏度
- < 10 pg/mL
-
组件
-
96-well plate precoated with antibody
lyophilized recombinant standard
biotinylated antibody (dilution 1:100)
Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
Sample diluent buffer
Antibody diluent buffer
ABC diluent buffer
TMB color developing agent
TMB stop solution
Adhesive cover
-
-
Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) ELISA Kit
ENPP2 适用: 人 Colorimetric Sandwich ELISA 93.75 pg/mL - 6000 pg/mL Plasma, Serum, Tissue Homogenate
Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) ELISA KitENPP2 适用: 小鼠 Colorimetric Sandwich ELISA 78 pg/mL - 5000 pg/mL Plasma, Serum, Tissue Homogenate
Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) ELISA KitENPP2 适用: 大鼠 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate
-
-
实验时间
- 15 min
-
板类型
- Pre-coated
-
限制
- 仅限研究用
-
-
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
-
有效期
- 12 months
-
-
- ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))
-
别名
- ENPP2
-
背景
-
Synonyms: Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, E-NPP 2, Autotaxin, Extracellular lysophospholipase D, LysoPLD, ENPP2, ATX, PDNP2
Tissue Specificity: Predominantly expressed in brain, placenta, ovary, and small intestine. Expressed in a number of carcinomas such as hepatocellular and prostate carcinoma, neuroblastoma and non-small-cell lung cancer. Expressed in body fluids such as plasma, cerebral spinal fluid (CSF), saliva, follicular and amniotic fluids. Not detected in leukocytes. Isoform 1 is more highly expressed in peripheral tissues than in the central nervous system (CNS). Adipocytes only express isoform 1. Isoform 3 is more highly expressed in the brain than in peripheral tissues.
Background: Autotaxin, also known as ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (E-NPP 2), is an enzyme that in humans is encoded by the ENPP2 gene. The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.
Cellular Localisation: Secreted. -
UniProt
- Q13822
抗原 See all ENPP2 ELISA试剂盒
-
