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PF4 ELISA 试剂盒

This 大鼠 PF4 ELISA Kit is a Colorimetric ELISA Kit designed to quantify 大鼠 PF4.
产品编号 ABIN5692208
发货至: 中国

Quick Overview for PF4 ELISA 试剂盒 (ABIN5692208)

抗原

See all PF4 ELISA试剂盒
PF4 (Platelet Factor 4 (PF4))

抗原表位

AA 30-105

适用

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大鼠

检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

156 pg/mL - 10000 pg/mL

应用范围

ELISA

样品类型

Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
  • 最低检测浓度

    156 pg/mL

    原理

    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Rat CXCL4/PF4. 96wells/kit, with removable strips.

    品牌

    PicoKine™

    Analytical Method

    Quantitative

    特异性

    Expression system for standard: E.coli, Immunogen sequence: V30-S105

    灵敏度

    < 15 pg/mL

    组件

    96-well plate precoated with antibody
    lyophilized recombinant standard
    biotinylated antibody (dilution 1:100)
    Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
    Sample diluent buffer
    Antibody diluent buffer
    ABC diluent buffer
    TMB color developing agent
    TMB stop solution
    Adhesive cover
  • 实验时间

    15 min

    板类型

    Pre-coated

    限制

    仅限研究用
  • 储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

    有效期

    12 months
  • 抗原 See all PF4 ELISA试剂盒

    PF4 (Platelet Factor 4 (PF4))

    别名

    Pf4

    背景

    Synonyms: Platelet factor 4, PF-4, C-X-C motif chemokine 4, Pf4, Cxcl4, Scyb4

    Background: Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4). The PF4 gene was localized on 4q12-q13. Chemokines play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair.

    Cellular Localisation: Secreted.

    UniProt

    P06765
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