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ARTN ELISA 试剂盒

ARTN 适用: 人 AA 108-220 Colorimetric Sandwich ELISA 62.5 pg/mL - 4000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
产品编号 ABIN5692196
发货至: 中国
  • 抗原 See all ARTN ELISA试剂盒
    ARTN (Artemin (ARTN))
    抗原表位
    AA 108-220
    适用
    • 5
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    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    检测范围
    62.5 pg/mL - 4000 pg/mL
    最低检测浓度
    62.5 pg/mL
    应用范围
    ELISA
    原理
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Artemin. 96wells/kit, with removable strips.
    品牌
    PicoKine™
    样品类型
    Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
    Analytical Method
    Quantitative
    特异性
    Expression system for standard: E.coli, Immunogen sequence: A108-G220
    灵敏度
    < 2 pg/mL
    组件
    96-well plate precoated with antibody
    lyophilized recombinant standard
    biotinylated antibody (dilution 1:100)
    Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
    Sample diluent buffer
    Antibody diluent buffer
    ABC diluent buffer
    TMB color developing agent
    TMB stop solution
    Adhesive cover
    Featured
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    Discover our top product ARTN ELISA Kit
  • 实验时间
    15 min
    板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    有效期
    12 months
  • 抗原 See all ARTN ELISA试剂盒
    ARTN (Artemin (ARTN))
    别名
    ARTN (ARTN 产品)
    别名
    ARTN ELISA Kit, ENOVIN ELISA Kit, EVN ELISA Kit, NBN ELISA Kit, neublastin ELISA Kit, artemin ELISA Kit, ARTN ELISA Kit, Artn ELISA Kit
    背景

    Synonyms: Artemin, Enovin, Neublastin, ARTN, EVN

    Tissue Specificity: Ubiquitous. Expressed at high levels in peripheral tissues including prostate, placenta, pancreas, heart, kidney, pituitary gland, lung and testis. Expressed at low levels in the brain.

    Background: Artemin, also known as enovin or neublastin, is a protein that in humans is encoded by the ARTN gene. This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma.

    Cellular Localisation: Secreted.
    UniProt
    Q5T4W7
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