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AZGP1 ELISA 试剂盒

This 人 AZGP1 ELISA Kit is a Colorimetric ELISA Kit designed to quantify 人 AZGP1.
产品编号 ABIN5564198
发货至: 中国

Quick Overview for AZGP1 ELISA 试剂盒 (ABIN5564198)

抗原

See all AZGP1 ELISA试剂盒
AZGP1 (alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1))

适用

  • 6
  • 3
  • 2
  • 1

检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

0.9375-60 ng/mL

应用范围

ELISA

样品类型

Cell Culture Supernatant, Plasma, Serum
  • 最低检测浓度

    0.9375 ng/mL

    Analytical Method

    Quantitative

    特异性

    Detects human Zinc-alpha-2-glycoprotein.

    交叉反应

    无交叉反应

    小鼠

    交叉反应 (详细)

    Does not detect mouse Zinc-alpha-2-glycoprotein.

    灵敏度

    0.23 ng/mL

    产品特性

    Zinc-alpha-2-glycoprotein (human) TurboELISA Kit
    This assay is a less than 1 hour sandwich Enzyme Linked-Immunosorbent Assay (ELISA) for quantitative determination of human Zinc-alpha-2-glycoprotein in biological fluids. Zinc-alpha-2-glycoprotein (ZAG) was first identified in the 1960s, and it's name derives from its precipitation from human plasma upon the addition of zinc salts. ZAG has since been found in secretory epithelial cells and in a range of body fluids. ZAG is identical to a lipid mobilizing factor isolated from the urine of patients with cancer cachexia and stimulates lipolysis in in vitro and in vivo experiments. Due to its expression in, and secretion from adipocytes, ZAG is considered an adipokine. Recently, the clinical significance of ZAG has been clarified. ZAG expression in adipocytes is inversely related to fat mass, thus it is intimately involved in the maintenance of body weight in mice and humans. Epidemiological studies have uncovered an association between ZAG and plasma cholesterol. The non-synonymous single nucleotide polymorphism rs4215 in ZAG is associated with plasma cholesterol and obesity. Structurally ZAG possesses a class I major histocompatibility complex (MHC) protein fold. It is distinct from other members of this protein family in that it is soluble, rather than being anchored to plasma membranes, and it associates with prolactin inducible protein rather than beta2-microglobulin. Similar to peptide antigen-presenting class I MHC molecules, ZAG possesses an open apical groove between its alpha1 and alpha2 domain helices.
  • 说明

    TRADEMARKS - TurboELISA™ and Turbo-coated Plate™ are Trademarks of Adipogen Life Sciences.

    板类型

    Pre-coated

    限制

    仅限研究用
  • 储存条件

    4 °C

    储存方法

    Short Term Storage: +4°C
    Long Term Storage: +4°C
    12 months after the day of manufacturing. See expiry date on ELISA Kit box.
  • 抗原 See all AZGP1 ELISA试剂盒

    AZGP1 (alpha-2-Glycoprotein 1, Zinc-Binding (AZGP1))

    别名

    Zinc-alpha-2-glycoprotein

    UniProt

    P25311

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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