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IL1F9 ELISA 试剂盒

IL1F9 适用: 人 Colorimetric Sandwich ELISA 3.9-250 pg/mL Cell Culture Supernatant, Serum
产品编号 ABIN5564184
发货至: 中国
  • 抗原 See all IL1F9 ELISA试剂盒
    IL1F9 (Interleukin 1 Family Member 9 (IL1F9))
    适用
    • 2
    • 2
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    检测范围
    3.9-250 pg/mL
    最低检测浓度
    3.9 pg/mL
    应用范围
    ELISA
    样品类型
    Cell Culture Supernatant, Serum
    Analytical Method
    Quantitative
    特异性
    Detects natural and recombinant human IL-36gamma.
    交叉反应
    灵敏度
    3 pg/mL
    产品特性
    IL-36gamma (human) ELISA Kit
    Featured
    Discover our best selling IL1F9 ELISA Kit
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    Discover our top product IL1F9 ELISA Kit
  • 板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: +4°C
    12 months after the day of manufacturing. See expiry date on ELISA Kit box.
  • 抗原 See all IL1F9 ELISA试剂盒
    IL1F9 (Interleukin 1 Family Member 9 (IL1F9))
    别名
    IL-36gamma (IL1F9 产品)
    别名
    IL-1F9 ELISA Kit, IL-1H1 ELISA Kit, IL-1RP2 ELISA Kit, IL1E ELISA Kit, IL1F9 ELISA Kit, IL1H1 ELISA Kit, IL1RP2 ELISA Kit, Il36g ELISA Kit, Il1f9 ELISA Kit, RGD1563019 ELISA Kit, IL36G ELISA Kit, interleukin 36 gamma ELISA Kit, interleukin 1 family, member 9 ELISA Kit, interleukin 36, gamma ELISA Kit, interleukin-36 gamma ELISA Kit, IL36G ELISA Kit, Il1f9 ELISA Kit, Il36g ELISA Kit, LOC100065031 ELISA Kit
    背景
    IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) are members of the IL-1 cytokine family that bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1 and are inhibited by IL-36Ra. The expression of IL-36 cytokines occurs mainly in the lung and skin and can be derived from diverse epithelial cell types including keratinocytes, bronchial epithelium as well as macrophages, monocytes and different T cell subsets. IL-36 family members induce the production of pro-inflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23, thus promoting neutrophil influx, dendritic cell (DC) activation, polarization of T helper type 1 (Th1) and IL-17-producing T cells (alphabeta T cells and gammadelta T cells) and keratinocyte proliferation. Induction of IL-36gamma in macrophages upon M. tuberculosis infection and its role in the release of antimicrobial peptides has been proposed. IL-36gamma is also induced in the lung in various models of asthma and can be produced by bronchial epithelial cells in response to viral infection, smoke or inflammatory cytokines and plays an important role in asthmatic pulmonary inflammation. IL-36gamma might be a potential biomarker of Inflammatory Bowel Disease and is highly expressed in inflamed skin from psoriasis patients and in Allergic Contact Dermatitis. IL-36gamma serum levels are enhanced and correlate to psoriasis severity and response to treatment with anti-TNF.
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