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Glucagon ELISA 试剂盒

This Various Species Glucagon ELISA Kit is a Colorimetric ELISA Kit designed to quantify Various Species Glucagon in Plasma, Cell Culture Supernatant 和 Serum.
产品编号 ABIN5526763
发货至: 中国

Quick Overview for Glucagon ELISA 试剂盒 (ABIN5526763)

抗原

See all Glucagon (GCG) ELISA试剂盒
Glucagon (GCG)

适用

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Various Species

检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

8.42-5000 pg/mL

应用范围

ELISA

样品类型

Plasma, Cell Culture Supernatant, Serum
  • 最低检测浓度

    8.42 pg/mL

    原理

    This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of Glucagon.

    Analytical Method

    Quantitative

    特异性

    Glucagon

    组件

    plate, standard, diluent

    试剂未包括

    pipettes, tubes, reader
  • 样本量

    100 μL

    实验时间

    3 - 4 h

    板类型

    Pre-coated

    限制

    仅限研究用
  • 缓冲液

    0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • 抗原 See all Glucagon (GCG) ELISA试剂盒

    Glucagon (GCG)

    别名

    Glucagon

    背景

    Glucagon is a 29-amino acid polypeptide, produced by alpha cells of the pancreas. The polypeptide has a molecular weight of 3485 Da that plays a critical role in glucose metabolism and homeostasis. It works to raise the concentration of glucose in the bloodstream. It is also used as a medication to treat a number of health conditions. Its effect is opposite to that of insulin, which lowers the glucose. The pancreas releases glucagon when the concentration of glucose in the bloodstream falls too low. Glucagon causes the liver to convert stored glycogen into glucose, which is released into the bloodstream. High blood-glucose levels, on the other hand, stimulate the release of insulin. Glucagon allows glucose to be taken up and used by insulin-dependent tissues. Thus, glucagon and insulin are part of a feedback system that keeps blood glucose levels stable. Abnormally elevated levels of glucagon may be caused by pancreatic tumors, such as glucagonoma, symptoms of which include necrolytic migratory erythema, reduced amino acids, and hyperglycemia. It may occur alone or in the context of multiple endocrine neoplasia type 1.

    NCBI登录号

    NM_002054

    UniProt

    P01275

    途径

    Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling
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