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IL23R ELISA 试剂盒

This 小鼠 IL23R ELISA Kit is a Colorimetric ELISA Kit designed to quantify 小鼠 IL23R. This ELISA Kit has been cited in1 publication.
产品编号 ABIN5510751
发货至: 中国

Quick Overview for IL23R ELISA 试剂盒 (ABIN5510751)

抗原

See all IL23R ELISA试剂盒
IL23R (Interleukin 23 Receptor (IL23R))

抗原表位

AA 25-373

适用

  • 4
  • 1
  • 1
小鼠

检测方法

Colorimetric

实验类型

Sandwich ELISA

应用范围

ELISA
  • 原理

    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse IL-23R

    品牌

    PicoKine™

    Analytical Method

    Quantitative

    特异性

    Expression system for standard: NSO, Immunogen sequence: I25-I373

    交叉反应 (详细)

    There is no detectable cross-reactivity with other relevant proteins.

    产品特性

    Tissue Specificity: Expressed by Th1, Th2 and dendritic cells.

  • 板类型

    Pre-coated

    限制

    仅限研究用
  • 储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

    有效期

    12 months
  • Wang, Deng, Wang, Wu, Gu, Jiang, Li: "MicroRNA-155 in exosomes secreted from helicobacter pylori infection macrophages immunomodulates inflammatory response." in: American journal of translational research, Vol. 8, Issue 9, pp. 3700-3709, (2016) (PubMed).

  • 抗原 See all IL23R ELISA试剂盒

    IL23R (Interleukin 23 Receptor (IL23R))

    别名

    Il23r

    背景

    Protein Function: Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis (By similarity). .

    Background: Interleukin-23 subunit alpha is a protein that in humans is encoded by the IL23A gene. The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.

    Synonyms: Interleukin-23 receptor, IL-23 receptor, IL-23R, Il23r,

    Full Gene Name: interleukin 23 receptor

    Cellular Localisation: Cell membrane, Single-pass type I membrane protein.

    UniProt

    Q8K4B4

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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