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GDF2 ELISA 试剂盒

GDF2 适用: 小鼠 AA 319-428 Colorimetric Sandwich ELISA
产品编号 ABIN5510748
发货至: 中国
  • 抗原 See all GDF2 ELISA试剂盒
    GDF2 (Growth Differentiation Factor 2 (GDF2))
    抗原表位
    AA 319-428
    适用
    • 6
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    • 2
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    小鼠
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    应用范围
    ELISA
    原理
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse BMP-9
    品牌
    PicoKine™
    Analytical Method
    Quantitative
    特异性
    Expression system for standard: CHO, Immunogen sequence: S319-R428
    交叉反应 (详细)
    There is no detectable cross-reactivity with other relevant proteins.
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  • 板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    有效期
    12 months
  • 抗原 See all GDF2 ELISA试剂盒
    GDF2 (Growth Differentiation Factor 2 (GDF2))
    别名
    Gdf2 (GDF2 产品)
    别名
    bmp9 ELISA Kit, BMP-9 ELISA Kit, BMP9 ELISA Kit, Bmp9 ELISA Kit, DSL1 ELISA Kit, growth differentiation factor 2 ELISA Kit, gdf2 ELISA Kit, GDF2 ELISA Kit, Gdf2 ELISA Kit
    背景

    Protein Function: Potent circulating inhibitor of angiogenesis. Could be involved in bone formation. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.

    Background: Growth differentiation factor 2 (GDF2) also known as bone morphogenetic protein (BMP)-9 is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Homozygous null mice exhibit malformations of the vasculature and skeleton.

    Synonyms: Growth/differentiation factor 2, GDF-2, Bone morphogenetic protein 9, BMP-9, Gdf2, Bmp9,

    Full Gene Name: growth differentiation factor 2

    Cellular Localisation: Secreted.
    UniProt
    Q9WV56
    途径
    Transition Metal Ion Homeostasis
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