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GDF2 ELISA 试剂盒

This 小鼠 GDF2 ELISA Kit is a Colorimetric ELISA Kit designed to quantify 小鼠 GDF2.
产品编号 ABIN5510748
发货至: 中国

Quick Overview for GDF2 ELISA 试剂盒 (ABIN5510748)

抗原

See all GDF2 ELISA试剂盒
GDF2 (Growth Differentiation Factor 2 (GDF2))

抗原表位

AA 319-428

适用

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小鼠

检测方法

Colorimetric

实验类型

Sandwich ELISA

应用范围

ELISA
  • 原理

    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse BMP-9

    品牌

    PicoKine™

    Analytical Method

    Quantitative

    特异性

    Expression system for standard: CHO, Immunogen sequence: S319-R428

    交叉反应 (详细)

    There is no detectable cross-reactivity with other relevant proteins.
  • 板类型

    Pre-coated

    限制

    仅限研究用
  • 储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

    有效期

    12 months
  • 抗原 See all GDF2 ELISA试剂盒

    GDF2 (Growth Differentiation Factor 2 (GDF2))

    别名

    Gdf2

    背景

    Protein Function: Potent circulating inhibitor of angiogenesis. Could be involved in bone formation. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.

    Background: Growth differentiation factor 2 (GDF2) also known as bone morphogenetic protein (BMP)-9 is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Homozygous null mice exhibit malformations of the vasculature and skeleton.

    Synonyms: Growth/differentiation factor 2, GDF-2, Bone morphogenetic protein 9, BMP-9, Gdf2, Bmp9,

    Full Gene Name: growth differentiation factor 2

    Cellular Localisation: Secreted.

    UniProt

    Q9WV56

    途径

    Transition Metal Ion Homeostasis
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