CD166 ELISA 试剂盒
Quick Overview for CD166 ELISA 试剂盒 (ABIN5510729)
抗原
See all CD166 (ALCAM) ELISA试剂盒抗原表位
适用
检测方法
实验类型
应用范围
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原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Rat ALCAM
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品牌
- PicoKine™
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Analytical Method
- Quantitative
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特异性
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Expression system for standard: NSO
Immunogen sequence: W28-K527 -
交叉反应 （详细）
- There is no detectable cross-reactivity with other relevant proteins.
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产品特性
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Tissue Specificity: Strongest expression in the lung, then brain, liver, and kidney. Present in the somatosensory system, basal ganglia, cortex, olfactory system, and circumventricular organs.
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Activated Leukocyte Cell Adhesion Molecule (ALCAM) ELISA Kit
ALCAM 适用: 人 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Activated Leukocyte Cell Adhesion Molecule (ALCAM) ELISA KitALCAM 适用: 大鼠 Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate
Activated Leukocyte Cell Adhesion Molecule (ALCAM) ELISA KitALCAM 适用: 小鼠 Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate
Activated Leukocyte Cell Adhesion Molecule (ALCAM) ELISA KitALCAM 适用: 兔 Colorimetric Sandwich ELISA 0.781 ng/mL - 50 ng/mL Plasma, Serum, Tissue Homogenate
Activated Leukocyte Cell Adhesion Molecule (ALCAM) ELISA KitALCAM 适用: 大鼠 Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Activated Leukocyte Cell Adhesion Molecule (ALCAM) ELISA KitALCAM 适用: 人 AA 28-526 Colorimetric Sandwich ELISA 312-20000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
Activated Leukocyte Cell Adhesion Molecule (ALCAM) ELISA KitALCAM 适用: 小鼠 AA 28-527 Colorimetric Sandwich ELISA 156-10.000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
Activated Leukocyte Cell Adhesion Molecule (ALCAM) ELISA KitALCAM 适用: 小鼠 Colorimetric Sandwich ELISA 0.468 ng/mL - 30 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Activated Leukocyte Cell Adhesion Molecule (ALCAM) ELISA KitALCAM 适用: 人 Colorimetric Sandwich ELISA 312 pg/mL - 20000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
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板类型
- Pre-coated
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限制
- 仅限研究用
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
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有效期
- 12 months
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- CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))
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别名
- Alcam
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背景
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Protein Function: Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts. Promotes T-cell activation and proliferation via its interactions with CD6 (By similarity). Contributes to the formation and maturation of the immunological synapse via its interactions with CD6 (By similarity). Mediates homotypic interactions with cells that express ALCAM. Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction. Inhibits endothelial cell migration and promotes endothelial tube formation via homotypic interactions. Required for normal organization of the lymph vessel network. Required for normal hematopoietic stem cell engraftment in the bone marrow. Plays a role in hematopoiesis, required for normal numbers of hematopoietic stem cells in bone marrow. Promotes in vitro osteoblast proliferation and differentiation (By similarity). Promotes neurite extension, axon growth and axon guidance, axons grow preferentially on surfaces that contain ALCAM (By similarity). Mediates outgrowth and pathfinding for retinal ganglion cell axons (By similarity). .
Background: CD166 antigen is a 100-105 kD typeI transmembrane glycoprotein that is a member of the immunoglobulin superfamily of proteins. In humans it is encoded by the ALCAM gene. The human gene was mapped to chromosome 3q13.1-q13.2 by fluorescence in situ hybridization of cDNA probes to metaphase chromosomes. It is also called CD166 (cluster of differentiation 166), MEMD, SC-1/DM-GRASP/BEN in the chicken, and KG-CAM in the rat. This gene is expressed on activated T cells, activated monocytes, epithelial cells, fibroblasts, neurons, melanoma cells, and also in sweat and sebaceous glands. CD166 plays an important role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during intrathymic T cell development. Recently, CD166 has also been used as a potential cancer stem cell marker.
Synonyms: CD166 antigen,Activated leukocyte cell adhesion molecule,HB2 ,KG-CAM ,Protein MEMD,SB-10 antigen ,CD166,Alcam,
Full Gene Name: CD166 antigen
Cellular Localisation: Cell membrane, Single-pass type I membrane protein . Cell projection, axon . Cell projection, dendrite . Detected at the immunological synapse, i.e, at the contact zone between antigen-presenting dendritic cells and T-cells. Colocalizes with CD6 and the TCR/CD3 complex at the immunological synapse.. -
UniProt
- O35112
抗原 See all CD166 (ALCAM) ELISA试剂盒
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