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APCS ELISA 试剂盒

This 人 APCS ELISA Kit is a Colorimetric ELISA Kit designed to quantify 人 APCS.
产品编号 ABIN5510715
发货至: 中国

Quick Overview for APCS ELISA 试剂盒 (ABIN5510715)

抗原

See all APCS ELISA试剂盒
APCS (Amyloid P Component, Serum (APCS))

抗原表位

AA 20-223

适用

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检测方法

Colorimetric

实验类型

Sandwich ELISA

应用范围

ELISA
  • 原理

    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human SAP/PTX2

    品牌

    PicoKine™

    Analytical Method

    Quantitative

    特异性

    Expression system for standard: E.coli
    Immunogen sequence: H20-V223

    交叉反应 (详细)

    There is no detectable cross-reactivity with other relevant proteins.

    产品特性

    Tissue Specificity: Found in serum and urine. .

  • 板类型

    Pre-coated

    限制

    仅限研究用
  • 储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

    有效期

    12 months
  • 抗原 See all APCS ELISA试剂盒

    APCS (Amyloid P Component, Serum (APCS))

    别名

    APCS

    背景

    Protein Function: Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.

    Background: Amyloid P component, serum (SAP), also known as PTX2 or APCS, is the identical serum form of amyloid P component (AP), a 25 kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". It belongs to the pentraxins family, characterised by calcium dependent ligand binding and distinctive flattened i²-jellyroll structure similar to that of the legume lectins. This gene is mapped to 1q23.2. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

    Synonyms: Serum amyloid P-component,SAP,9.5S alpha-1-glycoprotein,Serum amyloid P-component(1-203),APCS,PTX2,

    Full Gene Name: Serum amyloid P-component

    Cellular Localisation: Secreted.

    UniProt

    P02743
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