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METRN ELISA 试剂盒

This 小鼠 METRN ELISA Kit is a Colorimetric ELISA Kit designed to quantify 小鼠 METRN.
产品编号 ABIN5510711
发货至: 中国

Quick Overview for METRN ELISA 试剂盒 (ABIN5510711)

抗原

See all METRN ELISA试剂盒
METRN (Meteorin, Glial Cell Differentiation Regulator (METRN))

抗原表位

AA 22-291

适用

  • 2
  • 1
  • 1
小鼠

检测方法

Colorimetric

实验类型

Sandwich ELISA

应用范围

ELISA
  • 原理

    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse Meteorin/METRN

    品牌

    PicoKine™

    Analytical Method

    Quantitative

    特异性

    Expression system for standard: NSO
    Immunogen sequence: G22-D291

    交叉反应 (详细)

    There is no detectable cross-reactivity with other relevant proteins.

    产品特性

    Tissue Specificity: Highly expressed in brain. Expressed in undifferentiated neural progenitors and in astrocyte lineage, particulary in Bergmann glia, a subtype of radial glia, and a few discrete neuronal populations residing in the superior colliculus, the ocular motor nucleus, the raphe and pontine nuclei, and in various thalamic nuclei. Weakly expressed in heart, kidney, skeletal muscle, spleen, testis, gut and lung. .

  • 板类型

    Pre-coated

    限制

    仅限研究用
  • 储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

    有效期

    12 months
  • 抗原 See all METRN ELISA试剂盒

    METRN (Meteorin, Glial Cell Differentiation Regulator (METRN))

    别名

    Metrn

    背景

    Protein Function: Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia. .

    Background: Meteorin, glial cell differentiation regulator is a protein that in humans is encoded by the METRN gene. The mouse Metrn gene is mapped to chromosome 17. It is concluded that meteorin acts directly on satellite glial cells to induce a change in morphology and that transformed satellite glial cells induce the secondary effect of neurite extension. In cerebellar explants, meteorin induced conversion of cerebellar astrocytes into radial glia and promoted astrocyte differentiation from embryonic day 11.5 cerebral cortex neurospheres.

    Synonyms: Meteorin,Hypoxia/reoxygenation regulatory factor,Metrn,Hyrac,

    Full Gene Name: Meteorin

    Cellular Localisation: Secreted.

    UniProt

    Q8C1Q4
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