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- 抗原 See all LDLR ELISA试剂盒
- LDLR (Low Density Lipoprotein Receptor (LDLR))
- 抗原表位
- AA 22-788
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适用
- 人
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 应用范围
- ELISA
- 原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human LDLR
- 品牌
- PicoKine™
- Analytical Method
- Quantitative
- 特异性
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Expression system for standard: NSO
Immunogen sequence: A22-R788 - 交叉反应 （详细）
- There is no detectable cross-reactivity with other relevant proteins.
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- Discover our best selling LDLR ELISA Kit
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- Discover our top product LDLR ELISA Kit
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Low Density Lipoprotein Receptor (LDLR) ELISA Kit
LDLR 适用: 人 Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Cell Lysate, Tissue Homogenate
Low Density Lipoprotein Receptor (LDLR) ELISA KitLDLR 适用: 小鼠 Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate
Low Density Lipoprotein Receptor (LDLR) ELISA KitLDLR 适用: 大鼠 Colorimetric Sandwich ELISA 0.313 ng/mL - 20 ng/mL Plasma, Serum, Tissue Homogenate
Low Density Lipoprotein Receptor (LDLR) ELISA KitLDLR 适用: 人 Colorimetric Sandwich ELISA 0.313 ng/mL - 20 ng/mL Plasma, Serum, Tissue Homogenate
Low Density Lipoprotein Receptor (LDLR) ELISA KitLDLR 适用: 人 Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Cell Culture Supernatant, Plasma, Serum
Low Density Lipoprotein Receptor (LDLR) ELISA KitLDLR 适用: 小鼠 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Lysate, Tissue Homogenate
Low Density Lipoprotein Receptor (LDLR) ELISA KitLDLR 适用: 小鼠 AA 22-790 Colorimetric Sandwich ELISA
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- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- 有效期
- 12 months
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- 抗原 See all LDLR ELISA试剂盒
- LDLR (Low Density Lipoprotein Receptor (LDLR))
- 别名
- LDLR (LDLR 产品)
- 别名
- FH ELISA Kit, FHC ELISA Kit, LDLCQ2 ELISA Kit, Hlb301 ELISA Kit, LDLRA ELISA Kit, LDLA ELISA Kit, LDL receptor-2 ELISA Kit, fhc ELISA Kit, ldlcq2 ELISA Kit, ldlr ELISA Kit, ldlr2-a ELISA Kit, LDL receptor 1 ELISA Kit, ldlr-a ELISA Kit, ldlr-b ELISA Kit, low density lipoprotein receptor ELISA Kit, low density lipoprotein receptor a ELISA Kit, low density lipoprotein receptor S homeolog ELISA Kit, low density lipoprotein receptor L homeolog ELISA Kit, LDLR ELISA Kit, Ldlr ELISA Kit, ldlra ELISA Kit, ldlr.S ELISA Kit, ldlr.L ELISA Kit
- 背景
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Protein Function: Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.
Background: The Low-Density Lipoprotein (LDL) Receptor is a mosaic protein of 839 amino acids (after removal of 21-amino acid signal peptide) that mediates the endocytosis of cholesterol-rich LDL. In humans, the LDL receptor protein is encoded by the LDLR gene. It belongs to the Low density lipoprotein receptor gene family. The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.
Synonyms: Low-density lipoprotein receptor,LDL receptor,LDLR,
Full Gene Name: Low-density lipoprotein receptor
Cellular Localisation: Cell membrane, Single-pass type I membrane protein. Endomembrane system, Single-pass type I membrane protein. Membrane, clathrin-coated pit, Single-pass type I membrane protein. Golgi apparatus. Early endosome. Late endosome. Cell surface. Lysosome. Found distributed from the plasma membrane to intracellular compartments. Localizes to the Golgi apparatus, early and late endosomes/lysosomes and cell surface in the presence of PCSK9. - UniProt
- P01130
- 途径
- Hepatitis C, Lipid Metabolism
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