GREM2 ELISA 试剂盒
Quick Overview for GREM2 ELISA 试剂盒 (ABIN5510698)
抗原
See all GREM2 ELISA试剂盒抗原表位
适用
检测方法
实验类型
应用范围
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原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human GREM2
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品牌
- PicoKine™
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Analytical Method
- Quantitative
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特异性
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Expression system for standard: E.coli
Immunogen sequence: R22-Q168 -
交叉反应 (详细)
- There is no detectable cross-reactivity with other relevant proteins.
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板类型
- Pre-coated
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限制
- 仅限研究用
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
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有效期
- 12 months
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- GREM2 (Gremlin 2 (GREM2))
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别名
- GREM2
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背景
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Protein Function: Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells (By similarity). .
Background: GREM2, also known as PRDC, is one of several BMP antagonists that regulate the functions of BMPs during embryonic development and tissue differentiation. BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. The PRDC gene is mapped to chromosome 1q43.
Synonyms: Gremlin-2,Cysteine knot superfamily 1, BMP antagonist 2,DAN domain family member 3,Protein related to DAN and cerberus,GREM2,CKTSF1B2, DAND3, PRDC,
Full Gene Name: Gremlin-2
Cellular Localisation: Secreted. -
UniProt
- Q9H772
抗原 See all GREM2 ELISA试剂盒
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