PRSS3 ELISA 试剂盒
Quick Overview for PRSS3 ELISA 试剂盒 (ABIN5510696)
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适用
检测方法
实验类型
应用范围
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原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Pan Trypsin
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品牌
- PicoKine™
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Analytical Method
- Quantitative
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特异性
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Expression system for standard: NSO
Immunogen sequence: A16-S247 -
交叉反应 （详细）
- There is no detectable cross-reactivity with other relevant proteins.
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产品特性
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Tissue Specificity: Expressed in pancreas and brain. Also expressed in Paneth cells, at the base of small intestinal crypts. .
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Protease, serine, 3 (PRSS3) ELISA Kit
PRSS3 适用: 人 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Plasma, Serum, Tissue Homogenate
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板类型
- Pre-coated
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限制
- 仅限研究用
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
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有效期
- 12 months
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- PRSS3 (Protease, serine, 3 (PRSS3))
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别名
- PRSS3
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背景
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Protein Function: Digestive protease specialized for the degradation of trypsin inhibitors. In the ileum, may be involved in defensin processing, including DEFA5. .
Background: Trypsin is a serine protease from the PA clan superfamily, found in the digestive system of many vertebrates, where it hydrolyses proteins. In the duodenum, trypsin catalyzes the hydrolysis of peptide bonds, breaking down proteins into smaller peptides. The peptide products are then further hydrolyzed into amino acids via other proteases, rendering them available for absorption into the blood stream. Tryptic digestion is a necessary step in protein absorption as proteins are generally too large to be absorbed through the lining of the small intestine. Additionally, Trypsin is produced as the inactive zymogen trypsinogen in the pancreas. When the pancreas is stimulated by cholecystokinin, it is then secreted into the first part of the small intestine (the duodenum) via the pancreatic duct. Once in the small intestine, the enzyme enteropeptidase activates trypsinogen into trypsin by proteolytic cleavage. Auto catalysis can happen with trypsin using trypsinogen as the substrate. This activation mechanism is common for most serine proteases, and serves to prevent autodegradation of the pancreas.
Synonyms: Trypsin-3,3.4.21.4,Brain trypsinogen,Mesotrypsinogen,Serine protease 3,Serine protease 4,Trypsin III,Trypsin IV,PRSS3,PRSS4, TRY3, TRY4,
Full Gene Name: Trypsin-3
Cellular Localisation: Secreted. -
UniProt
- P35030
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