GDF5 ELISA 试剂盒
Quick Overview for GDF5 ELISA 试剂盒 (ABIN5510677)
抗原
See all GDF5 ELISA试剂盒抗原表位
适用
检测方法
实验类型
应用范围
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原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse GDF5
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品牌
- PicoKine™
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Analytical Method
- Quantitative
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特异性
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Expression system for standard: E.coli
Immunogen sequence: A376-R495 -
交叉反应 （详细）
- There is no detectable cross-reactivity with other relevant proteins.
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Growth Differentiation Factor 5 (GDF5) ELISA Kit
GDF5 适用: 人 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Growth Differentiation Factor 5 (GDF5) ELISA KitGDF5 适用: 小鼠 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Growth Differentiation Factor 5 (GDF5) ELISA KitInstant GDF5 适用: 人 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Growth Differentiation Factor 5 (GDF5) ELISA KitGDF5 适用: 大鼠 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Growth Differentiation Factor 5 (GDF5) ELISA KitGDF5 适用: Cow AA 376-495 Colorimetric Sandwich ELISA
Growth Differentiation Factor 5 (GDF5) ELISA KitGDF5 适用: 马 AA 376-495 Colorimetric Sandwich ELISA
Growth Differentiation Factor 5 (GDF5) ELISA KitGDF5 适用: 猴 AA 376-495 Colorimetric Sandwich ELISA
Growth Differentiation Factor 5 (GDF5) ELISA KitGDF5 适用: Pig AA 376-495 Colorimetric Sandwich ELISA
Growth Differentiation Factor 5 (GDF5) ELISA KitGDF5 适用: 小鸡 AA 376-495 Colorimetric Sandwich ELISA
Growth Differentiation Factor 5 (GDF5) ELISA KitGDF5 适用: Hamster AA 376-495 Colorimetric Sandwich ELISA
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板类型
- Pre-coated
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限制
- 仅限研究用
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
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有效期
- 12 months
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- GDF5 (Growth Differentiation Factor 5 (GDF5))
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别名
- Gdf5
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背景
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Protein Function: Growth factor involved in bone and cartilage formation. During cartilage development regulates differentiation of chondrogenic tissue through two pathways. Firstly, positively regulates differentiation of chondrogenic tissue through its binding of high affinity with BMPR1B and of less affinity with BMPR1A, leading to induction of SMAD1-SMAD5-SMAD8 complex phosphorylation and then SMAD protein signaling transduction (By similarity). Secondly, negatively regulates chondrogenic differentiation through its interaction with NOG (By similarity). Required to prevent excessive muscle loss upon denervation. This function requires SMAD4 and is mediated by phosphorylated SMAD1/5/8 (PubMed:24076600). Binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response, including TNF secretion by monocytes (By similarity). .
Background: Growth/differentiation factor 5 is a protein that in humans is encoded by the GDF5 gene. GDF5 is a protein belonging to the transforming growth factor beta superfamily that is expressed in the developing central nervous system, and has a role in skeletal and joint development. It also increases the survival of neurones that respond to the neurotransmitter dopamine, and is a potential therapeutic molecule associated with Parkinson's disease.
Synonyms: Growth/differentiation factor 5,GDF-5,Bone morphogenetic protein 14,BMP-14,Gdf5,Bmp14, Bp, Gdf-5,
Full Gene Name: Growth/differentiation factor 5
Cellular Localisation: Secreted . Cell membrane. -
UniProt
- P43027
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