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CPB2 ELISA 试剂盒

CPB2 适用: 人 AA 1-423 Colorimetric Sandwich ELISA
产品编号 ABIN5510667
发货至: 中国
  • 抗原 See all CPB2 ELISA试剂盒
    CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
    抗原表位
    AA 1-423
    适用
    • 7
    • 3
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    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    应用范围
    ELISA
    原理
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human TAFI/CPB2
    品牌
    PicoKine™
    Analytical Method
    Quantitative
    特异性
    Expression system for standard: NSO
    Immunogen sequence: M1-V423
    交叉反应 (详细)
    There is no detectable cross-reactivity with other relevant proteins.
    产品特性

    Tissue Specificity: Plasma, synthesized in the liver.

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  • 板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    有效期
    12 months
  • 抗原 See all CPB2 ELISA试剂盒
    CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
    别名
    CPB2 (CPB2 产品)
    别名
    CPU ELISA Kit, PCPB ELISA Kit, TAFI ELISA Kit, 1110032P04Rik ELISA Kit, 4930405E17Rik ELISA Kit, AI255929 ELISA Kit, CPR ELISA Kit, Cpu ELISA Kit, pCPB ELISA Kit, zgc:112493 ELISA Kit, carboxypeptidase B2 ELISA Kit, carboxypeptidase B2 (plasma) ELISA Kit, CPB2 ELISA Kit, Cpb2 ELISA Kit, cpb2 ELISA Kit
    背景

    Protein Function: Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down- regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. .

    Background: Carboxypeptidase B2 (CPB2), also known as carboxypeptidase U (CPU), plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), is an enzyme that, in humans, is encoded by the gene CPB2. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen. When it is activated by proteolysis at residue Arg92 by the thrombin/thrombomodulin complex, CPB2 exhibits carboxypeptidase activity. Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.

    Synonyms: Carboxypeptidase B2,3.4.17.20 ,Carboxypeptidase U,CPU,Plasma carboxypeptidase B,pCPB,Thrombin-activable fibrinolysis inhibitor,TAFI,CPB2,

    Full Gene Name: Carboxypeptidase B2

    Cellular Localisation: Secreted.
    UniProt
    Q96IY4
    途径
    Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis
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