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Quick Overview for CPB2 ELISA 试剂盒 (ABIN5510667)
抗原
See all CPB2 ELISA试剂盒抗原表位
适用
检测方法
实验类型
应用范围
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原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human TAFI/CPB2
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Analytical Method
- Quantitative
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特异性
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Expression system for standard: NSO
Immunogen sequence: M1-V423 -
交叉反应 （详细）
- There is no detectable cross-reactivity with other relevant proteins.
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产品特性
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Tissue Specificity: Plasma, synthesized in the liver.
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Carboxypeptidase B2 (Plasma) (CPB2) ELISA Kit
CPB2 适用: 小鼠 Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Plasma
Carboxypeptidase B2 (Plasma) (CPB2) ELISA KitCPB2 适用: 人 Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Plasma
Carboxypeptidase B2 (Plasma) (CPB2) ELISA KitCPB2 适用: 人 Colorimetric Sandwich ELISA 3.125 ng/mL - 200 ng/mL Plasma, Serum, Tissue Homogenate
Carboxypeptidase B2 (Plasma) (CPB2) ELISA KitCPB2 适用: 马 Colorimetric Sandwich ELISA 3.125 ng/mL - 200 ng/mL Plasma, Serum, Tissue Homogenate
Carboxypeptidase B2 (Plasma) (CPB2) ELISA KitCPB2 适用: 大鼠 Colorimetric Sandwich ELISA 1.563 ng/mL - 100 ng/mL Plasma, Serum, Tissue Homogenate
Carboxypeptidase B2 (Plasma) (CPB2) ELISA KitCPB2 适用: 小鼠 Colorimetric Sandwich ELISA 0.781 ng/mL - 50 ng/mL Plasma, Serum, Tissue Homogenate
Carboxypeptidase B2 (Plasma) (CPB2) ELISA KitCPB2 适用: 大鼠 Colorimetric Sandwich ELISA 0.78 ng/mL - 50 ng/mL Plasma
Carboxypeptidase B2 (Plasma) (CPB2) ELISA KitCPB2 适用: 人 Colorimetric Competition ELISA 31.25-2000 ng/mL Plasma, Tissue Homogenate
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板类型
- Pre-coated
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限制
- 仅限研究用
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
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有效期
- 12 months
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- CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
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别名
- CPB2
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背景
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Protein Function: Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down- regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. .
Background: Carboxypeptidase B2 (CPB2), also known as carboxypeptidase U (CPU), plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), is an enzyme that, in humans, is encoded by the gene CPB2. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen. When it is activated by proteolysis at residue Arg92 by the thrombin/thrombomodulin complex, CPB2 exhibits carboxypeptidase activity. Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.
Synonyms: Carboxypeptidase B2,3.4.17.20 ,Carboxypeptidase U,CPU,Plasma carboxypeptidase B,pCPB,Thrombin-activable fibrinolysis inhibitor,TAFI,CPB2,
Full Gene Name: Carboxypeptidase B2
Cellular Localisation: Secreted. -
UniProt
- Q96IY4
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途径
- Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis
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