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EDIL3 ELISA 试剂盒

DEL1 适用: 人 AA 24-480 Colorimetric Sandwich ELISA
产品编号 ABIN5510665
发货至: 中国
  • 抗原 See all EDIL3 (DEL1) ELISA试剂盒
    EDIL3 (DEL1) (EGF like repeats and discoidin domains 3 (DEL1))
    抗原表位
    AA 24-480
    适用
    • 4
    • 1
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    应用范围
    ELISA
    原理
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human EDIL3
    品牌
    PicoKine™
    Analytical Method
    Quantitative
    特异性
    Expression system for standard: NSO
    Immunogen sequence: D24-E480
    交叉反应 (详细)
    There is no detectable cross-reactivity with other relevant proteins.
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    Discover our top product DEL1 ELISA Kit
  • 板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    有效期
    12 months
  • 抗原 See all EDIL3 (DEL1) ELISA试剂盒
    EDIL3 (DEL1) (EGF like repeats and discoidin domains 3 (DEL1))
    别名
    EDIL3 (DEL1 产品)
    别名
    si:dkey-84i7.1 ELISA Kit, Del1 ELISA Kit, XDel1 ELISA Kit, DEL1 ELISA Kit, Del-1 ELISA Kit, EGF-like repeats and discoidin I-like domains 3a ELISA Kit, EGF like repeats and discoidin domains 3 L homeolog ELISA Kit, EGF like repeats and discoidin domains 3 ELISA Kit, EGF-like repeats and discoidin I-like domains 3 ELISA Kit, edil3a ELISA Kit, edil3.L ELISA Kit, EDIL3 ELISA Kit, Edil3 ELISA Kit
    背景

    Protein Function: Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development.

    Background: EDIL3, also known as DEL1, is a glycoprotein that is secreted by endothelial cells and can associate with the endothelial cell surface and the extracellular matrix. It is regulated by hypoxia or vascular injury and has been implicated in vascular remodeling during angiogenesis. The EDIL3 gene is mapped to 5q14. Human endothelial cells bind to Del1 together with the alpha-V (ITGAV)/beta-3 (ITGB3) integrin receptor. It is confirmed that adhesion of endothelial cells to Del1 is integrin mediated and that Del1 binds ITGAV/ITGB3. Functional analysis showed that both Del1 and vitronectin (VTN) stimulate endothelial cell migration. Immunoprecipitation and immunoblot analyses revealed that adhesion of endothelial cells to Del1 induces tyrosine phosphorylation of PTK2.

    Synonyms: EGF-like repeat and discoidin I-like domain-containing protein 3,Developmentally-regulated endothelial cell locus 1 protein,Integrin-binding protein DEL1,EDIL3,DEL1,

    Full Gene Name: EGF-like repeat and discoidin I-like domain-containing protein 3

    Cellular Localisation: Secreted.
    UniProt
    O43854
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