EDIL3 ELISA 试剂盒
Quick Overview for EDIL3 ELISA 试剂盒 (ABIN5510665)
抗原
See all EDIL3 (DEL1) ELISA试剂盒抗原表位
适用
检测方法
实验类型
应用范围
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原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human EDIL3
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品牌
- PicoKine™
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Analytical Method
- Quantitative
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特异性
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Expression system for standard: NSO
Immunogen sequence: D24-E480 -
交叉反应 （详细）
- There is no detectable cross-reactivity with other relevant proteins.
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EGF like repeats and discoidin domains 3 (DEL1) ELISA Kit
DEL1 适用: 人 Colorimetric Sandwich ELISA 125 pg/mL - 8000 pg/mL Plasma, Serum, Tissue Homogenate
EGF like repeats and discoidin domains 3 (DEL1) ELISA KitDEL1 适用: 小鼠 Colorimetric Sandwich ELISA 28 pg/mL - 1800 pg/mL Cell Culture Supernatant, Plasma, Serum, Tissue Homogenate
EGF like repeats and discoidin domains 3 (DEL1) ELISA KitDEL1 适用: 人 Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Cell Lysate, Tissue Homogenate
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板类型
- Pre-coated
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限制
- 仅限研究用
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
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有效期
- 12 months
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- EDIL3 (DEL1) (EGF like repeats and discoidin domains 3 (DEL1))
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别名
- EDIL3
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背景
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Protein Function: Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development.
Background: EDIL3, also known as DEL1, is a glycoprotein that is secreted by endothelial cells and can associate with the endothelial cell surface and the extracellular matrix. It is regulated by hypoxia or vascular injury and has been implicated in vascular remodeling during angiogenesis. The EDIL3 gene is mapped to 5q14. Human endothelial cells bind to Del1 together with the alpha-V (ITGAV)/beta-3 (ITGB3) integrin receptor. It is confirmed that adhesion of endothelial cells to Del1 is integrin mediated and that Del1 binds ITGAV/ITGB3. Functional analysis showed that both Del1 and vitronectin (VTN) stimulate endothelial cell migration. Immunoprecipitation and immunoblot analyses revealed that adhesion of endothelial cells to Del1 induces tyrosine phosphorylation of PTK2.
Synonyms: EGF-like repeat and discoidin I-like domain-containing protein 3,Developmentally-regulated endothelial cell locus 1 protein,Integrin-binding protein DEL1,EDIL3,DEL1,
Full Gene Name: EGF-like repeat and discoidin I-like domain-containing protein 3
Cellular Localisation: Secreted. -
UniProt
- O43854
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