MUC16 ELISA 试剂盒
(1 reference)Quick Overview for MUC16 ELISA 试剂盒 (ABIN5510649)
抗原
See all MUC16 (CA125) ELISA试剂盒抗原表位
适用
检测方法
实验类型
应用范围
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原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human CA125/MUC16
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品牌
- PicoKine™
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Analytical Method
- Quantitative
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特异性
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Expression system for standard: CHO
Immunogen sequence: M21005-Q21992 -
交叉反应 （详细）
- There is no detectable cross-reactivity with other relevant proteins.
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产品特性
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Tissue Specificity: Expressed in corneal and conjunctival epithelia (at protein level). Overexpressed in ovarian carcinomas and ovarian low malignant potential (LMP) tumors as compared to the expression in normal ovarian tissue and ovarian adenomas. .
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Mucin 16, Cell Surface Associated (CA125) ELISA Kit
CA125 适用: 人 Colorimetric Sandwich ELISA 1.56 U/mL - 100 U/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Mucin 16, Cell Surface Associated (CA125) ELISA KitCA125 适用: 小鼠 Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Plasma, Serum, Tissue Homogenate
Mucin 16, Cell Surface Associated (CA125) ELISA KitCA125 适用: 大鼠 Colorimetric Sandwich ELISA 7.813 IU/mL - 500 IU/mL Plasma, Serum, Tissue Homogenate
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板类型
- Pre-coated
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限制
- 仅限研究用
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
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有效期
- 12 months
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: "TGFβ1 in fibroblasts-derived exosomes promotes epithelial-mesenchymal transition of ovarian cancer cells." in: Oncotarget, Vol. 8, Issue 56, pp. 96035-96047, (2017) (PubMed).
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: "TGFβ1 in fibroblasts-derived exosomes promotes epithelial-mesenchymal transition of ovarian cancer cells." in: Oncotarget, Vol. 8, Issue 56, pp. 96035-96047, (2017) (PubMed).
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- MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))
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别名
- MUC16
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背景
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Protein Function: Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. .
Background: CA-125, also known as mucin 16 or MUC16, is a protein that in humans is encoded by the MUC16 gene. MUC16 is a member of the mucin family glycoproteins. It is a component of the ocular surface, the respiratory tract and the female reproductive tract epithelia. Since MUC16 is highly glycosylated it creates a hydrophilic environment that acts as a lubricating barrier against foreign particles and infectious agents on the apical membrane of epithelial cells. Also, the cytoplasmic tail of MUC16 has been shown to interact with cytoskeleton by binding members of the ERM protein family. The expression of mucin 16 has been shown to be altered in dry eye, cystic fibrosis, and several types of cancers.
Synonyms: Mucin-16 ,MUC-16,Ovarian cancer-related tumor marker CA125 ,CA-125 ,Ovarian carcinoma antigen CA125 ,MUC16 ,CA125 ,
Full Gene Name: Mucin-16
Cellular Localisation: Cell membrane, Single-pass type I membrane protein. Secreted, extracellular space. May be liberated into the extracellular space following the phosphorylation of the intracellular C-terminus which induces the proteolytic cleavage and liberation of the extracellular domain. -
UniProt
- Q8WXI7
抗原 See all MUC16 (CA125) ELISA试剂盒
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