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WFDC2 ELISA 试剂盒

Cited in 1 publication. This 人 WFDC2 ELISA Kit specifically detects WFDC2 .
产品编号 ABIN5510648
发货至: 中国
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Quick Overview for WFDC2 ELISA 试剂盒 (ABIN5510648)

抗原

See all WFDC2 ELISA试剂盒
WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))

抗原表位

AA 31-124

适用

  • 8
  • 2
  • 1
  • 1
  • 1

检测方法

Colorimetric

实验类型

Sandwich ELISA

应用范围

ELISA
  • 原理

    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human HE4

    Analytical Method

    Quantitative

    特异性

    Expression system for standard: E.coli
    Immunogen sequence: E31-F124

    交叉反应 (详细)

    There is no detectable cross-reactivity with other relevant proteins.

    产品特性

    Tissue Specificity: Expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. Highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis. .

  • 板类型

    Pre-coated

    限制

    仅限研究用
  • 储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

    有效期

    12 months
  • Dong, Liu, Li: "Value of HE4 Combined with Cancer Antigen 125 in the Diagnosis of Endometrial Cancer." in: Pakistan journal of medical sciences, Vol. 33, Issue 4, pp. 1013-1017, (2017) (PubMed).

  • 抗原 See all WFDC2 ELISA试剂盒

    WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))

    别名

    WFDC2

    背景

    Protein Function: Broad range protease inhibitor. .

    Background: WAP four-disulfide core domain protein 2, also known as Human Epididymis Protein 4 (HE4), is a protein that in humans is encoded by the WFDC2 gene. This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.

    Synonyms: WAP four-disulfide core domain protein 2,Epididymal secretory protein E4,Major epididymis-specific protein E4,Putative protease inhibitor WAP5,WFDC2,HE4, WAP5,

    Full Gene Name: WAP four-disulfide core domain protein 2

    Cellular Localisation: Secreted.

    UniProt

    Q14508
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